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Articles Published Processes
12/16/2021 7:46:10 AM | Browse: 721 | Download: 1706
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Received |
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2021-07-07 10:16 |
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Peer-Review Started |
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2021-07-07 10:16 |
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First Decision by Editorial Office Director |
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2021-07-28 04:52 |
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Return for Revision |
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2021-07-28 04:52 |
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Revised |
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2021-08-09 14:17 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2021-12-06 03:29 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2021-12-08 06:07 |
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Articles in Press |
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2021-12-08 06:07 |
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Edit the Manuscript by Language Editor |
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2021-09-25 18:55 |
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Typeset the Manuscript |
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2021-12-13 06:43 |
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Publish the Manuscript Online |
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2021-12-16 07:46 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Basic Study |
| Article Title |
Inhibitory effect of maspinon neovascularization in diabetic retinopathy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Feng Qiu and Hui-Juan Tong |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Liaoning Province Natural Science Foundation |
2020-BS-277 |
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| Corresponding Author |
Hui-Juan Tong, PhD, Assistant Professor, Department of Nursing, Shenyang Medical College, No. 146 North Huanghe Avenue, Shenyang 110034, Liaoning Province, China. thj_9921@163.com |
| Key Words |
Maspin; Diabetic retinopathy; Neovascularization; Vascular endothelial growth factor; Hypoxia-inducible factor 1-alpha |
| Core Tip |
The aim of our study was to evaluate the effectiveness of intravitreal injection of recombinant human maspin on neovascularization in diabetic retinopathy. A mouse model of oxygen-induced retinopathy was used to simulate neovascularization in diabetic retinopathy. Maspin inhibited neovascularization in this model by modulating the hypoxia-inducible factor 1-alpha/vascular endothelial growth factor pathway, which provides a potential and effective strategy for the treatment of diabetic retinopathy. |
| Publish Date |
2021-12-16 07:46 |
| Citation |
Qiu F, Tong HJ. Inhibitory effect of maspin on neovascularization in diabetic retinopathy. World J Diabetes 2021; 12(12): 2050-2057 |
| URL |
https://www.wjgnet.com/1948-9358/full/v12/i12/2050.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i12.2050 |
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