| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Comparison of tumor regression grading systems for locally advanced gastric adenocarcinoma after neoadjuvant chemotherapy
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zi-Ning Liu, Yin-Kui Wang, Li Zhang, Yong-Ning Jia, Shan Fei, Xiang-Ji Ying, Yan Zhang, Shuang-Xi Li, Yu Sun, Zi-Yu Li and Jia-Fu Ji |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Beijing Municipal Health Commission |
DFL20181103 |
| Beijing Municipal Health Commission |
ZYLX201701 |
|
| Corresponding Author |
Zi-Yu Li, MD, PhD, Professor, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Gastrointestinal Cancer Center, Peking University Cancer Hospital and Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. ziyu_li@hsc.pku.edu.cn |
| Key Words |
Gastric cancer; Neoadjuvant chemotherapy; Tumor regression grade; Survival; Concordance index |
| Core Tip |
Current Tumor regression grade (TRG) evaluations are based on various systems bringing confusion to oncologists and pathologists when interpreting results in similar clinical contexts. On the other hand, the recent six-tier system tumor regression grade (JGCA2017-TRG) recommended by Japanese Gastric Cancer Association (JGCA) is investigational. This is the first report of the use of c-index to evaluate predictive accuracies of five published TRG systems in gastric cancer. With a satisfying sample size, our results gave clinicians a better understanding of the TRG, especially the residual tumor percentage, in gastric cancer, and furthermore alleviate the oncologists and pathologists workload. |
| Publish Date |
2021-12-14 23:58 |
| Citation |
Liu ZN, Wang YK, Zhang L, Jia YN, Fei S, Ying XJ, Zhang Y, Li SX, Sun Y, Li ZY, Ji JF. Comparison of tumor regression grading systems for locally advanced gastric adenocarcinoma after neoadjuvant chemotherapy. World J Gastrointest Oncol 2021; 13(12): 2161-2179 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i12/2161.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i12.2161 |
