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Articles Published Processes
12/27/2021 5:24:00 AM | Browse: 423 | Download: 951
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Received |
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2021-05-27 12:27 |
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Peer-Review Started |
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2021-05-27 12:27 |
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To Make the First Decision |
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Return for Revision |
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2021-07-06 01:59 |
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Revised |
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2021-07-07 14:40 |
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Second Decision |
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2021-11-22 03:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-11-25 02:26 |
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Articles in Press |
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2021-11-25 02:26 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-12-13 08:56 |
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Publish the Manuscript Online |
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2021-12-27 05:24 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Retrospective Study |
| Article Title |
Use of oral vancomycin in children with autoimmune liver disease: A single centre experience
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Angelo Di Giorgio, Anna Tulone, Emanuele Nicastro, Lorenzo Norsa, Aurelio Sonzogni and Lorenzo D'Antiga |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Angelo Di Giorgio, MD, PhD, N/A, N/A, Pediatric Hepatology, Gastroenterology and Transplantation, Hospital Papa Giovanni XXIII , Piazza Oms 1, Bergamo 24127, Italy. adigiorgio@asst-pg23.it |
| Key Words |
Autoimmune hepatitis; Autoimmune sclerosing cholangitis; Autoimmune liver disease; Vancomycin; Children; Liver transplantation |
| Core Tip |
Experience with oral vancomycin in children with autoimmune liver disease (AILD) is limited. We enrolled 75 children [median age 10.5 years (5.6-13.4)], 54 with autoimmune hepatitis and 21 with autoimmune sclerosing cholangitis; 63/75 achieved remission by standard immunosuppressive (IS) therapy, whereas 12/75 (16%) required oral vancomycin treatment (OVT). In 6/12 patients (50%) the response was complete, whereas it was partial in 2/12 (17%), and absent in 4/12 (33%). Overall OVT increased the remission rate of the whole group of AILD patients from 81% to 92%. OVT may represent a valuable treatment option in children with AILD who do not respond to standard IS. |
| Publish Date |
2021-12-27 05:24 |
| Citation |
Di Giorgio A, Tulone A, Nicastro E, Norsa L, Sonzogni A, D'Antiga L. Use of oral vancomycin in children with autoimmune liver disease: A single centre experience. World J Hepatol 2021; 13(12): 2113-2127 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i12/2113.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i12.2113 |
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