Publication Name	World Journal of Virology
Manuscript ID	68481
Country	Austria

Received	2021-05-24 16:35
Peer-Review Started	2021-05-24 16:39
To Make the First Decision
Return for Revision	2021-06-17 05:36
Revised	2021-06-23 23:57
Second Decision	2021-12-09 03:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-12-10 03:09
Articles in Press	2021-12-10 03:09
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-12-06 18:46
Typeset the Manuscript	2022-01-07 03:53
Publish the Manuscript Online	2022-01-15 07:06

ISSN	2220-3249 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Neurosciences
Manuscript Type	Letter to the Editor
Article Title	Repurposing the antioxidant and anti-inflammatory agent N-acetyl cysteine for treating COVID-19
Manuscript Source	Unsolicited Manuscript
All Author List	Josef Finsterer, Fulvio A Scorza, Carla A Scorza and Ana C Fiorini
ORCID	Author(s) ORCID Number Josef Finsterer http://orcid.org/0000-0003-2839-7305 Fulvio A Scorza http://orcid.org/0000-0002-0694-8674 Carla A Scorza http://orcid.org/0000-0001-7810-4748 Ana C Fiorini http://orcid.org/0000-0003-2989-2308
Funding Agency and Grant Number
Corresponding Author	Josef Finsterer, MD, Lecturer, Neurological Department, Messerli Institute, Postfach 20, Vienna 1180, Austria. fipaps@yahoo.de
Key Words	N-acetyl cysteine; SARS-CoV-2; COVID-19; Reactive oxygen species; Cytokines
Core Tip	N-acetyl cysteine (NAC) is a well-known antioxidant and anti-inflammatory agent that has been considered beneficial in the treatment of coronavirus disease 2019 (COVID-19). Though previous studies in patients with chronic lung disease, chronic heart disease, immune-mediated disease, viral infections, and malignancy have shown promising results, there is currently no clinical evidence that NAC prevents COVID-19, alleviates the severity of COVID-19, or improves the overall outcome of COVID-19 patients.
Publish Date	2022-01-15 07:06
Citation	Finsterer J, Scorza FA, Scorza CA, Fiorini AC. Repurposing the antioxidant and anti-inflammatory agent N-acetyl cysteine for treating COVID-19. World J Virol 2022; 11(1): 82-84
URL	https://www.wjgnet.com/2220-3249/full/v11/i1/82.htm
DOI	https://dx.doi.org/10.5501/wjv.v11.i1.82

Full Article (PDF)	WJV-11-82.pdf
Full Article (Word)	WJV-11-82.docx
Manuscript File	68481_Auto_Edited-ZMG-Kerr C.docx
Answering Reviewers	68481-Answering reviewers.pdf
Audio Core Tip	68481-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	68481-Conflict-of-interest statement.pdf
Copyright License Agreement	68481-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	68481-Language certificate.pdf
Peer-review Report	68481-Peer-review(s).pdf
Scientific Misconduct Check	68481-Bing-Gao CC-1.jpg
Scientific Misconduct Check	68481-CrossCheck.png
Scientific Misconduct Check	68481-Bing-Gong ZM-2.png
CrossCheck Report	68481-CrossCheck report.pdf