Publication Name	World Journal of Gastroenterology
Manuscript ID	68582
Country	Italy

Received	2021-05-27 16:16
Peer-Review Started	2021-05-27 16:20
To Make the First Decision
Return for Revision	2021-06-21 06:13
Revised	2021-07-07 14:20
Second Decision	2021-12-09 03:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-12-10 02:45
Articles in Press	2021-12-10 02:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-12-02 16:52
Typeset the Manuscript	2021-12-17 04:02
Publish the Manuscript Online	2021-12-24 09:48

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Frontier
Article Title	Magnetic challenge against gastroesophageal reflux
Manuscript Source	Invited Manuscript
All Author List	Mauro Bortolotti
ORCID	Author(s) ORCID Number Mauro Bortolotti http://orcid.org/0000-0002-5273-9013
Funding Agency and Grant Number
Corresponding Author	Mauro Bortolotti, MD, N/A, Department of Internal Medicine and Gastroenterology, S. Orsola-Malpighi Polyclinic, University of Bologna, Via Massarenti 48, Bologna 40138, Italy. bormau@tin.it
Key Words	Gastro-esophageal reflux disease; Magnetic sphincter augmentation device; Nissen fundoplication; Angelchik prosthesis; Lower esophageal sphincter; Dysphagia
Core Tip	The idea of a magnetic device aimed to prevent gastroesophageal reflux was conceived and realized more or less 15 years ago, for which it is time to take stock and consider its future. The first and only device available nowadays in the market is the Linx magnetic sphincter augmentation. Its effectiveness was examined and compared to that of Nissen fundoplication, whereas its complications, similar to those of the Angelchik prosthesis, were described and their pathophysiology discussed. Furthermore, the pros and cons of the upcoming magnetic anti-reflux devices were examined, underlining the fact that, working with a mechanism completely different to that of the first device, many of its complications could be avoided.
Publish Date	2021-12-24 09:48
Citation	Bortolotti M. Magnetic challenge against gastroesophageal reflux. World J Gastroenterol 2021; 27(48): 8227-8241
URL	https://www.wjgnet.com/1007-9327/full/v27/i48/8227.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i48.8227

Full Article (PDF)	WJG-27-8227.pdf
Full Article (Word)	WJG-27-8227.docx
Manuscript File	68582_Auto_Edited-JJ Wang-Webster J.docx
Answering Reviewers	68582-Answering reviewers.pdf
Audio Core Tip	68582-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	68582-Conflict-of-interest statement.pdf
Copyright License Agreement	68582-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	68582-Language certificate.pdf
Supplementary Material	68582-Copyright permission.pdf
Peer-review Report	68582-Peer-review(s).pdf
Scientific Misconduct Check	68582-Bing-Wang JJ-2.png
Scientific Editor Work List	68582-Scientific editor work list.pdf