Publication Name	World Journal of Gastroenterology
Manuscript ID	6947
Country	China

Received	2013-10-30 20:02
Peer-Review Started	2013-11-01 10:12
To Make the First Decision	2013-12-04 09:18
Return for Revision	2013-12-05 19:10
Revised
Second Decision	2014-03-13 13:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-13 16:41
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-08 14:50
Publish the Manuscript Online	2014-06-06 16:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: Disease and treatments
Manuscript Source	Invited Manuscript
All Author List	Tung On Yau, Ceen-Ming Tang and Jun Yu
Funding Agency and Grant Number	Funding Agency Grant Number National Basic Research Program of China (973 Program) 2010CB529305 Innovation and Technology Support Programme, Hong Kong ITS/214/12
Corresponding Author	Jun Yu, MD, PhD, Professor, Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, LKS Institute of Health Sciences, The Chinese University of Hong Kong, Room 707A, Li Ka Shing Medical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong, China. junyu@cuhk.edu.hk
Key Words	Epstein-Barr virus; Gastric carcinoma; Epigenetic dysregulation; Aberrant DNA methylation; Epigenetic therapies
Core Tip	Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC) comprises nearly 10% of gastric carcinoma cases worldwide. In the present review, we critically discuss the role of EBV in gastric carcinogenesis, summarising the role of viral proteins and microRNAs) with respect to aberrant methylation in EBVaGC. Given the role of epigenetic dysregulation in tumourigenesis, epigenetic modifiers may represent a novel therapeutic strategy.
Publish Date	2014-06-06 16:55
Citation	Yau TO, Tang CM, Yu J. Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: Disease and treatments. World J Gastroenterol 2014; 20(21): 6448-6456
URL	http://www.wjgnet.com/1007-9327/full/v20/i21/6448.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i21.6448

Full Article (PDF)	WJG-20-6448.pdf
Full Article (Word)	WJG-20-6448.doc
Manuscript File	6947-Review.docx
Answering Reviewers	6947-Answering reviewers.pdf
Copyright License Agreement	6947-Copyright assignment.pdf
Peer-review Report	6947-Peer reviewer(s).pdf
Scientific Editor Work List	6947-Scientific editor work list.doc