Publication Name	World Journal of Clinical Cases
Manuscript ID	69695
Country	China

Received	2021-07-08 15:12
Peer-Review Started	2021-07-08 15:15
To Make the First Decision
Return for Revision	2021-07-26 07:28
Revised	2021-07-30 15:09
Second Decision	2021-09-08 03:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-09-08 09:57
Articles in Press	2021-09-08 09:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-09-17 16:14
Typeset the Manuscript	2021-11-15 02:18
Publish the Manuscript Online	2021-11-22 10:34

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Hematology
Manuscript Type	Case Report
Article Title	Persistent fibrinogen deficiency after snake bite: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Meng-Hao Xu, Jing Li, Liang Han and Chao Chen
ORCID	Author(s) ORCID Number Meng-Hao Xu http://orcid.org/0000-0002-2795-263X Jing Li http://orcid.org/0000-0002-1346-5355 Liang Han http://orcid.org/0000-0003-4161-444X Chao Chen http://orcid.org/0000-0001-6099-4527
Funding Agency and Grant Number
Corresponding Author	Chao Chen, MD, PhD, Doctor, Doctor, Research Fellow, Surgeon, Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. chenchao027@163.com
Key Words	Snake bite; Coagulation disorders; Venom-induced consumption coagulopathy; Fibrinogen deficiency; Fibrinogen infusion therapy; Case report
Core Tip	Venom-induced consumption coagulopathy (VICC) is characterized by decreased coagulation factor activity and fibrinogen deficiency. Hemorrhage-inducing snake venom contains several ingredients that directly or indirectly consume fibrinogen through multiple mechanisms. We here report a rare case with persistent afibrinogenemia without abnormal coagulation factor activity after a viper bite. Our report may assist the diagnosis and treatment of fibrinogen deficiency in patients with VICC.
Publish Date	2021-11-22 10:34
Citation	Xu MH, Li J, Han L, Chen C. Persistent fibrinogen deficiency after snake bite: A case report. World J Clin Cases 2021; 9(33): 10355-10361
URL	https://www.wjgnet.com/2307-8960/full/v9/i33/10355.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i33.10355

Full Article (PDF)	WJCC-9-10355.pdf
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CARE Checklist–2016	69695-CARE-Checklist–2016-revision_5837.pdf
Manuscript File	69695_Auto_Edited_Kerr C_Clear Copy.docx
Answering Reviewers	69695-Answering reviewers.pdf
Audio Core Tip	69695-Audio core tip.m4a
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Scientific Editor Work List	69695-Scientific editor work list.pdf
CrossCheck Report	69695-CrossCheck report.pdf