Publication Name	World Journal of Gastroenterology
Manuscript ID	7006
Country	France

Received	2013-10-31 15:51
Peer-Review Started	2013-10-31 20:34
To Make the First Decision	2013-12-16 18:03
Return for Revision	2013-12-17 13:49
Revised	2014-01-08 07:28
Second Decision	2014-01-20 18:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-20 19:18
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-19 18:01
Publish the Manuscript Online	2014-04-14 10:49

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Colorectal cancer and immunity: What we know and perspectives
Manuscript Source	Invited Manuscript
All Author List	Simon Pernot, Magali Terme, Thibault Voron, Orianne Colussi, Elie Marcheteau, Eric Tartour and Julien Taieb
Funding Agency and Grant Number
Corresponding Author	Dr. Julien Taieb, Service d’Hépatogastro-entérologie et d’oncologie digestive, Hôpital Européen Georges-Pompidou, Université Paris Descartes, Sorbonne Paris Cité 20, rue Leblanc, 75015 Paris, France. julien.taieb@egp.aphp.fr
Key Words	Colorectal cancer; Immunotherapy; Immunity; Immunoregulation; Vaccination
Core Tip	Immune system is now widely accepted as a key mechanism to prevent occurrence of cancer and intratumoral T CD8+ and CD45+ lymphocytes infiltrate has shown to be a major prognosis factor in colorectal cancer. However, immunity fail in controlling tumor growth, because of strong escape mechanisms to the immune system developed by the tumor. In recent years, several immunotherapy strategies have been tested in colorectal cancer. This review provides an understanding of the mechanisms involved and identifies innovating therapeutic strategies.
Publish Date	2014-04-14 10:49
Citation	Pernot S, Terme M, Voron T, Colussi O, Marcheteau E, Tartour E, Taieb J. Colorectal cancer and immunity: What we know and perspectives. World J Gastroenterol 2014; 20(14): 3738-3750
URL	http://www.wjgnet.com/1007-9327/full/v20/i14/3738.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i14.3738

Full Article (PDF)	WJG-20-3738.pdf
Full Article (Word)	WJG-20-3738.doc
Manuscript File	7006-Review.doc
Answering Reviewers	7006-Answering reviewers.pdf
Copyright License Agreement	7006-Copyright assignment.pdf
Peer-review Report	7006-Peer review(s).pdf
Scientific Editor Work List	7006-Scientific editor work list.doc