Publication Name	World Journal of Clinical Cases
Manuscript ID	70233
Country	China

Received	2021-07-27 11:41
Peer-Review Started	2021-07-27 11:48
To Make the First Decision
Return for Revision	2021-10-22 08:52
Revised	2021-11-02 03:39
Second Decision	2022-02-08 05:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-02-10 10:33
Articles in Press	2022-02-10 10:33
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-01-24 12:14
Typeset the Manuscript	2022-02-27 12:39
Publish the Manuscript Online	2022-03-11 00:39

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Case Report
Article Title	Treatment and five-year follow-up of type A insulin resistance syndrome: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Yong-Hua Chen, Qing-Qing Chen and Chun-Lin Wang
ORCID	Author(s) ORCID Number Yong-Hua Chen http://orcid.org/0000-0001-6621-1466 Qing-Qing Chen http://orcid.org/0000-0003-4295-6871 Chun-Lin Wang http://orcid.org/0000-0002-8288-3075
Funding Agency and Grant Number
Corresponding Author	Chun-Lin Wang, Doctor, PhD, Chief Doctor, Professor, Pediatrics, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun RD.,Shangchcheng District, Hangzhou 310003, Zhejiang Province, China. hzwangcl@zju.edu.cn
Key Words	Type A insulin resistance syndrome; Treatment; Pioglitazone; Flutamide; Case report
Core Tip	Type A insulin resistance syndrome (TAIRS) is a rare disorder characterized by severe insulin resistance due to defects in signaling through the insulin receptor. We present the rare case of a female patient aged 11 years and 9 mo who had type A insulin resistance with an INSR heterozygous mutation (c.3614C>T). This is the first case report describing the use of pioglitazone and flutamide used in combination in a child with TAIRS. This protocol for TAIRS is inexpensive, effective, and free of side effects.
Publish Date	2022-03-11 00:39
Citation	Chen Y, Chen Q, Wang CL. Treatment and five-year follow-up of type A insulin resistance syndrome: A case report. World J Clin Cases 2022; 10(8): 2522-2528
URL	https://www.wjgnet.com/2307-8960/full/v10/i8/2522.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i8.2522

Full Article (PDF)	WJCC-10-2522.pdf
Full Article (Word)	WJCC-10-2522.docx
Manuscript File	70233_Auto_Edited-YJM-Webster JR.docx
Answering Reviewers	70233-Answering reviewers.pdf
Audio Core Tip	70233-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	70233-Conflict-of-interest statement.pdf
Copyright License Agreement	70233-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	70233-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	70233-Language certificate.pdf
Peer-review Report	70233-Peer-review(s).pdf
Scientific Misconduct Check	70233-Bing-Ma YJ-2.png
Scientific Editor Work List	70233-Scientific editor work list.pdf
CrossCheck Report	70233-CrossCheck Report.pdf