Publication Name	World Journal of Gastroenterology
Manuscript ID	7061
Country	India

Received	2013-11-02 15:14
Peer-Review Started	2013-11-04 16:56
First Decision by Editorial Office Director
Return for Revision	2013-12-17 19:48
Revised	2014-01-07 16:06
Publication Fee Transferred
Second Decision by Editor	2014-02-20 09:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-02-20 09:23
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-03 10:41
Publish the Manuscript Online	2014-03-12 14:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Irritable bowel syndrome and small intestinal bacterial overgrowth: Meaningful association or unnecessary hype
Manuscript Source	Invited Manuscript
All Author List	Uday C Ghoshal and Deepakshi Srivastava
Funding Agency and Grant Number
Corresponding Author	Uday C Ghoshal, MD, DNB, DM, FACG, RFF, Professor, Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India. udayghoshal@gmail.com
Key Words	Glucose hydrogen breath test; Lactulose hydrogen breath test; Functional bowel disease; Dysbiosis; Gut flora
Core Tip	Irritable bowel syndrome (IBS) has been conventionally thought to be a disorder without an organic basis. However, recently data are emerging to show that it may have organic basis at least in a subset of patients. Though several studies reported an association between small intestinal bacterial overgrowth (SIBO) and IBS, the frequency of SIBO reported to vary between 4% and 78%. The current review suggests that the association between SIBO and IBS is definite, but the studies reporting high prevalence of SIBO in IBS over-estimated its frequency due to use of fallacious diagnostic methods. Better test to diagnose SIBO in patients with IBS is highly needed.
Publish Date	2014-03-12 14:46
Citation	Ghoshal UC, Srivastava D. Irritable bowel syndrome and small intestinal bacterial overgrowth: Meaningful association or unnecessary hype. World J Gastroenterol 2014; 20(10): 2482-2491
URL	http://www.wjgnet.com/1007-9327/full/v20/i10/2482.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i10.2482

Full Article (PDF)	WJG-20-2482.pdf
Full Article (Word)	WJG-20-2482.doc
Manuscript File	7061-Review.docx
Answering Reviewers	7061-Answering Reviews.pdf
Copyright License Agreement	7061-Copyright assignment.pdf
Peer-review Report	7061-Peer review(s).pdf
Scientific Editor Work List	7061-Scientific editor work list.doc