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Publication Name World Journal of Gastroenterology
Manuscript ID 7061
Country/Territory India
2013-11-02 15:14
Peer-Review Started
2013-11-04 16:56
To Make the First Decision
2013-12-16 17:30
Return for Revision
2013-12-17 19:48
2014-01-07 16:06
Second Decision
2014-02-20 09:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-02-20 09:23
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-03-03 10:41
Publish the Manuscript Online
2014-03-12 14:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Irritable bowel syndrome and small intestinal bacterial overgrowth: Meaningful association or unnecessary hype
Manuscript Source Invited Manuscript
All Author List Uday C Ghoshal and Deepakshi Srivastava
Funding Agency and Grant Number
Corresponding author Uday C Ghoshal, MD, DNB, DM, FACG, RFF, Professor, Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India. udayghoshal@gmail.com
Keywords Glucose hydrogen breath test; Lactulose hydrogen breath test; Functional bowel disease; Dysbiosis; Gut flora
Core Tip Irritable bowel syndrome (IBS) has been conventionally thought to be a disorder without an organic basis. However, recently data are emerging to show that it may have organic basis at least in a subset of patients. Though several studies reported an association between small intestinal bacterial overgrowth (SIBO) and IBS, the frequency of SIBO reported to vary between 4% and 78%. The current review suggests that the association between SIBO and IBS is definite, but the studies reporting high prevalence of SIBO in IBS over-estimated its frequency due to use of fallacious diagnostic methods. Better test to diagnose SIBO in patients with IBS is highly needed.
Publish Date 2014-03-12 14:46
Citation Ghoshal UC, Srivastava D. Irritable bowel syndrome and small intestinal bacterial overgrowth: Meaningful association or unnecessary hype. World J Gastroenterol 2014; 20(10): 2482-2491
Url http://www.wjgnet.com/1007-9327/full/v20/i10/2482.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i10.2482
Full Article (PDF) WJG-20-2482.pdf
Full Article (Word) WJG-20-2482.doc
Manuscript File 7061-Review.docx
Answering Reviewers 7061-Answering Reviews.pdf
Copyright License Agreement 7061-Copyright assignment.pdf
Peer-review Report 7061-Peer review(s).pdf
Scientific Editor Work List 7061-Scientific editor work list.doc