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Articles Published Processes
2/23/2022 3:51:54 PM | Browse: 367 | Download: 646
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Received |
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2021-08-24 15:39 |
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Peer-Review Started |
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2021-08-24 15:40 |
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To Make the First Decision |
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Return for Revision |
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2021-11-17 02:41 |
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Revised |
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2021-11-27 02:08 |
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Second Decision |
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2022-01-17 05:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-20 04:44 |
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Articles in Press |
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2022-01-20 04:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-02-15 07:28 |
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Publish the Manuscript Online |
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2022-02-23 15:51 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Opinion Review |
| Article Title |
Gut-brain axis: Focus on gut metabolites short-chain fatty acids
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cen Guo, Yajing Huo, Yu Li, Yan Han and Da Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
81800510 |
| Shanghai Sailing Program |
18YF1415900 |
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| Corresponding Author |
Da Zhou, MD, PhD, Attending Doctor, Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai Institute of Liver Disease, Fenglin Rd No.180, Shanghai, 200032 200032, China. zhou.da@zs-hospital.sh.cn |
| Key Words |
Gut-brain axis; Short-chain fatty acids; Neurological disease; Microbiome-gut-brain |
| Core Tip |
Recently, emerging evidence suggests that short-chain fatty acids (SCFAs) exert crucial functions on the brain. The levels of SCFAs can change in many neurological disorders such as Parkinson’s disease, Alzheimer’s disease, autism spectrum disorder, major depressive disorder, stroke, epilepsy, multiple sclerosis, and so on. Meanwhile, SCFAs might play a role in the pathogenesis of these diseases. In this review, we outline possible pathways of microbiota–gut–brain (MGB) axis, the interactions between SCFAs and MGB axis, as well as their relationships with different central neurological diseases, which helps to better understand the biological roles of SCFAs in neurological disorders via MGB axis and shed light on potential therapeutic approaches for these neurological disorders. |
| Publish Date |
2022-02-23 15:51 |
| Citation |
Guo C, Huo YJ, Li Y, Han Y, Zhou D. Gut-brain axis: Focus on gut metabolites short-chain fatty acids. World J Clin Cases 2022; 10(6): 1754-1763 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i6/1754.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i6.1754 |
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