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Articles Published Processes
3/15/2022 2:23:07 PM | Browse: 781 | Download: 1483
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Received |
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2021-08-30 04:16 |
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Peer-Review Started |
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2021-08-30 04:18 |
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First Decision by Editorial Office Director |
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2021-10-03 19:09 |
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Return for Revision |
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2021-10-03 19:09 |
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Revised |
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2021-10-24 04:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-02-21 07:27 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-02-23 20:56 |
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Articles in Press |
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2022-02-23 20:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-03-08 17:58 |
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Publish the Manuscript Online |
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2022-03-15 14:23 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Minireviews |
| Article Title |
Humanin and diabetes mellitus: A review of in vitro and in vivo studies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chrysoula Boutari, Panagiotis D Pappas, Theodoros D Theodoridis and Dimitrios Vavilis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Chrysoula Boutari, MD, MSc, PhD, Manager, Doctor, Doctor, Instructor, Postdoc, Second Propedeutic Department of Internal Medicine, Hippocration Hospital, Aristotle University of Thessaloniki, 49, Konstantinoupoleos Street, Thessaloniki 54642, Greece. chrisoulabgr@yahoo.gr |
| Key Words |
Diabetes mellitus; Insulin resistance; Humanin; Aging; Apoptosis; Oxidative stress |
| Core Tip |
Humanin (HN) exerts cyto-protective and anti-apoptotic effects. Type 2 diabetes mellitus (T2DM) is considered an age-related disease. Beyond the role of HN against age-related diseases, it increases insulin sensitivity, improves the survival of pancreatic beta cells, and delays the onset of diabetes. Altered HN levels could serve as a potential biomarker in prediabetes and T2DM, since they seem to be an effect or a response to the increased reactive oxygen species production, oxidative stress, and reduced mitochondrial DNA copy number-A major and important question is whether HN could be used as a potential therapeutic option for diabetes. |
| Publish Date |
2022-03-15 14:23 |
| Citation |
Boutari C, Pappas PD, Theodoridis TD, Vavilis D. Humanin and diabetes mellitus: A review of in vitro and in vivo studies. World J Diabetes 2022; 13(3): 213-223 |
| URL |
https://www.wjgnet.com/1948-9358/full/v13/i3/213.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v13.i3.213 |
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