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Articles Published Processes
4/30/2022 5:08:22 AM | Browse: 198 | Download: 455
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Received |
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2021-09-01 00:14 |
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Peer-Review Started |
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2021-09-01 00:18 |
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To Make the First Decision |
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Return for Revision |
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2021-11-11 08:04 |
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Revised |
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2021-11-23 00:46 |
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Second Decision |
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2022-03-14 05:29 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-03-16 16:19 |
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Articles in Press |
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2022-03-16 16:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-04-19 02:15 |
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Publish the Manuscript Online |
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2022-04-30 05:08 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Effect of Xuebijing injection on myocardium during cardiopulmonary bypass: A prospective, randomized, double blind trial
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhe-Hao Jin, Xiao-Qing Zhao, Hai-Bin Sun, Jing-Li Zhu and Wei Gao |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wei Gao, MD, Doctor, Department of Anesthesiology, 2nd Affiliated Hospital of Harbin Medical University, No.246 Xuefu Road,Nangang District, Harbin 150001, Heilongjiang Province, China. gaowei20055@126.com |
| Key Words |
Xuebijing injection; Cardiopulmonary bypass; Cardiac injury; Cardioprotection; Circulating inflammation; Oxidative stress |
| Core Tip |
Xuebijing injection (XBJ) significantly reduced myocardial injury in patients undergoing cardiopulmonary bypass (CPB), as demonstrated by significantly lower levels of myocardial injury markers including troponin I and creatine kinase-MB, and the preserved cardiac ejection fraction in patients in the XBJ group compared with those in the control group. The benefit of XBJ against myocardial injury was accompanied by reduced serum concentrations of inflammatory markers, including tumor necrosis factor-α, interleukin (IL)-1β and IL-8 and an increase in anti-inflammatory factor IL-10. These results suggest that perioperative XBJ is associated with attenuated cardiac injury during CPB, likely via anti-inflammatory and antioxidative mechanisms. |
| Publish Date |
2022-04-30 05:08 |
| Citation |
Jin ZH, Zhao XQ, Sun HB, Zhu JL, Gao W. Effect of Xuebijing injection on myocardium during cardiopulmonary bypass: A prospective, randomized, double blind trial. World J Clin Cases 2022; 10(13): 4110-4118 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i13/4110.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i13.4110 |
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