Publication Name	World Journal of Gastroenterology
Manuscript ID	7133
Country	Mexico

Received	2013-11-05 22:23
Peer-Review Started	2013-11-06 15:59
To Make the First Decision	2013-12-26 11:30
Return for Revision	2014-01-06 11:43
Revised	2014-04-10 00:00
Second Decision	2014-06-13 11:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-13 12:49
Articles in Press	2014-06-13 13:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-22 08:49
Publish the Manuscript Online	2014-09-07 13:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Evidence-Based Medicine
Article Title	PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis
Manuscript Source	Invited Manuscript
All Author List	Mario Pelaez-Luna, Guillermo Robles-Diaz, Samuel Canizales-Quinteros and Maria T Tusié-Luna
Funding Agency and Grant Number
Corresponding Author	Mario Pelaez-Luna, MD, Associate Professor of Medicine, Research Division, School of Medicine, UNAM, Pancreas Clinic-Gastroenterology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Colonia Sección XVI, Tlalpan, Mexico City, CP 14000, Mexico. mariopl@prodigy.net.mx
Key Words	Cationic trypsinogen; SPINK1; PRSS1; Chronic pancreatitis; Recurrent acute pancreatitis; Hereditary pancreatitis
Core Tip	Chronic and recurrent idiopathic pancreatitis has been associated with mutations in genes responsible for the synthesis of pancreatic proteases (PRSS1) and protease inhibitors (SPINK1). The distribution of these mutations varies among countries, but has not been examined in detail in Latin American countries. This study examined PRSS1 and SPINK1 in 19 Mexican subjects with chronic pancreatitis and/or idiopathic recurrent acute pancreatitis and identified two novel PRSS1 mutations and one novel SPINK1 mutation.
Publish Date	2014-09-07 13:31
Citation	Pelaez-Luna M, Robles-Diaz G, Canizales-Quinteros S, Tusié-Luna MT. PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis. World J Gastroenterol 2014; 20(33): 11788-11792
URL	http://www.wjgnet.com/1007-9327/full/v20/i33/11788.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i33.11788

Full Article (PDF)	WJG-20-11788.pdf
Full Article (Word)	WJG-20-11788.doc
Manuscript File	7133-Review.docx
Answering Reviewers	7133-Answering review.pdf
Copyright License Agreement	7133-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7133-Language certificate.pdf
Peer-review Report	7133-Peer review.pdf
Scientific Misconduct Check	7133-Corsscheck.jpg
Scientific Editor Work List	7133-Scientific editor work list.pdf