| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Validation model of fibrosis-8 index score to predict significant fibrosis among patients with nonalcoholic fatty liver disease
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Thaninee Prasoppokakorn, Wah-Kheong Chan, Vincent Wai-Sun Wong, Panyavee Pitisuttithum, Sanjiv Mahadeva, Nik Raihan Nik Mustapha, Grace Lai-Hung Wong, Howard Ho-Wai Leung, Pimsiri Sripongpun and Sombat Treeprasertsuk |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Fatty Liver Research Fund, Faculty of Medicine Foundation, Chulalongkorn University |
|
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| Corresponding Author |
Sombat Treeprasertsuk, MD, PhD, Instructor, Professor, Department of Medicine, Division of Gastroenterology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, King Chulalongkorn Memorial Hospital 1873 Rama 4 Road, Pathumwan District, Bangkok 10330, Thailand. battan5410@gmail.com |
| Key Words |
Nonalcoholic fatty liver disease; Fibrosis 8 score; Fibrosis 4 score; Nonalcoholic fatty liver disease fibrosis score |
| Core Tip |
Noninvasive diagnosis of hepatic fibrosis is crucial for nonalcoholic fatty liver disease (NAFLD). The Fibrosis 8 score (FIB-8) score was recently developed by incorporating four additional variables into the Fibrosis 4 score (FIB-4) score. The diagnostic performance of the FIB-8 score exhibited higher accuracy in diagnosing significant fibrosis (≥ F2) than the NAFLD fibrosis score but was not superior to the FIB-4 score in our Asian cohort population. We postulated that gamma-glutamyl transferase might be an additional variable that predicts significant fibrosis in NAFLD patients. |
| Publish Date |
2022-04-15 08:25 |
| Citation |
Prasoppokakorn T, Chan WK, Wong VWS, Pitisuttithum P, Mahadeva S, Nik Mustapha NR, Wong GLH, Leung HHW, Sripongpun P, Treeprasertsuk S. Validation model of fibrosis-8 index score to predict significant fibrosis among patients with nonalcoholic fatty liver disease. World J Gastroenterol 2022; 28(15): 1563-1573 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i15/1563.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i15.1563 |
