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3/17/2022 3:25:03 AM | Browse: 315 | Download: 534
Publication Name World Journal of Gastroenterology
Manuscript ID 72437
Country Italy
Received
2021-10-15 18:25
Peer-Review Started
2021-10-15 18:27
To Make the First Decision
Return for Revision
2021-12-12 06:37
Revised
2021-12-24 16:33
Second Decision
2022-02-17 05:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-02-20 12:37
Articles in Press
2022-02-20 12:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-02-08 01:44
Typeset the Manuscript
2022-03-08 21:49
Publish the Manuscript Online
2022-03-17 03:25
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Rectal neuroendocrine tumors: Current advances in management, treatment, and surveillance
Manuscript Source Invited Manuscript
All Author List Camilla Gallo, Roberta Elisa Rossi, Federica Cavalcoli, Federico Barbaro, Ivo Boškoski, Pietro Invernizzi and Sara Massironi
ORCID
Author(s) ORCID Number
Camilla Gallo http://orcid.org/0000-0002-7598-7220
Roberta Elisa Rossi http://orcid.org/0000-0003-4208-4372
Federica Cavalcoli http://orcid.org/0000-0002-7745-7573
Federico Barbaro http://orcid.org/0000-0002-7928-3757
Ivo Boškoski http://orcid.org/0000-0001-8194-2670
Pietro Invernizzi http://orcid.org/0000-0003-3262-1998
Sara Massironi http://orcid.org/0000-0003-3214-8192
Funding Agency and Grant Number
Corresponding Author Sara Massironi, MD, PhD, Doctor, Division of Gastroenterology and Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases, San Gerardo Hospital, Via Pergolesi, 33, Monza 20900, Italy. s.massironi@asst-monza.it
Key Words Rectal neuroendocrine tumors; Endoscopy; Endoscopic submucosal dissection; Resectable advanced disease; Systemic therapy
Core Tip Rectal neuroendocrine neoplasms (r-NENs) represent 1%-2% of all rectal tumors, but an increasing incidence rate has been recently reported. Up to 90% of r-NENs are < 10 mm in size, confined to the submucosa, and well-differentiated, so that the endoscopic resection represents their gold-standard therapy. Advanced metastatic NENs are usually poorly differentiated G3 carcinomas treated with chemotherapy, except for rare G1-G2 neoplasms, which can be targeted with less aggressive systemic options. Locally advanced r-NENs invading submucosal layers, with a ≥ 10 mm diameter, but still without distant metastases, represent the real therapeutic challenge among rectal tumors.
Publish Date 2022-03-17 03:25
Citation Gallo C, Rossi RE, Cavalcoli F, Barbaro F, Boškoski I, Invernizzi P, Massironi S. Rectal neuroendocrine tumors: Current advances in management, treatment, and surveillance. World J Gastroenterol 2022; 28(11): 1123-1138
URL https://www.wjgnet.com/1007-9327/full/v28/i11/1123.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i11.1123
Full Article (PDF) WJG-28-1123.pdf
Full Article (Word) WJG-28-1123.docx
Manuscript File 72437_Auto_Edited-YJM_WangTQ.docx
Answering Reviewers 72437-Answering reviewers.pdf
Audio Core Tip 72437-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 72437-Conflict-of-interest statement.pdf
Copyright License Agreement 72437-Copyright license agreement.pdf
Peer-review Report 72437-Peer-review(s).pdf
Scientific Editor Work List 72437-Scientific editor work list.pdf