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Articles Published Processes
5/26/2023 9:50:15 AM | Browse: 180 | Download: 388
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Received |
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2023-01-19 11:27 |
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Peer-Review Started |
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2023-01-19 11:30 |
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To Make the First Decision |
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Return for Revision |
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2023-03-07 08:06 |
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Revised |
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2023-03-21 15:08 |
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Second Decision |
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2023-04-12 03:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-12 08:17 |
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Articles in Press |
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2023-04-12 08:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-19 00:21 |
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Publish the Manuscript Online |
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2023-05-26 09:50 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Review |
| Article Title |
Impact of anastomotic leakage on long-term prognosis after colorectal cancer surgery
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Valeria Tonini and Manuel Zanni |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Valeria Tonini, MD, PhD, Full Professor, Surgeon, Surgical Oncologist, Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, Bologna 40138, Italy. valeria.tonini@unibo.it |
| Key Words |
Anastomotic leakage; Colorectal surgery; Colon cancer; Rectal cancer; Long term prognosis; Long term survival |
| Core Tip |
Colorectal cancer (CRC) is one of the most common malignancies in the world. Despite significant improvements in surgical technique, postoperative complications still occur in a fair percentage of patients undergoing colorectal surgery. The most feared complication is anastomotic leakage. It negatively affects short-term prognosis, with increased post-operative morbidity and mortality, higher hospitalization time and costs. Moreover, it may require further surgery with the creation of a permanent or temporary stoma. While there is no doubt about the negative impact of anastomotic dehiscence on the short-term prognosis of patients operated on for CRC, still under discussion is its impact on the long-term prognosis. Some authors have described an association between leakage and reduced overall survival, disease-free survival, and increased recurrence, while other authors have found no real impact of dehiscence on long term prognosis. The purpose of this paper is to review all the literature about the impact of anastomotic dehiscence on long-term prognosis after CRC surgery. The main risk factors of leakage and early detection markers are also summarized. |
| Publish Date |
2023-05-26 09:50 |
| Citation |
Tonini V, Zanni M. Impact of anastomotic leakage on long-term prognosis after colorectal cancer surgery. World J Gastrointest Surg 2023; 15(5): 745-756 |
| URL |
https://www.wjgnet.com/1948-9366/full/v15/i5/745.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v15.i5.745 |
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