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Articles Published Processes
6/17/2022 3:19:26 AM | Browse: 564 | Download: 1322
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Received |
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2021-11-03 08:51 |
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Peer-Review Started |
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2021-11-03 08:52 |
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First Decision by Editorial Office Director |
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2021-12-27 07:24 |
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Return for Revision |
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2021-12-27 07:24 |
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Revised |
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2022-01-10 08:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-04-24 02:51 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-04-24 19:39 |
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Articles in Press |
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2022-04-24 19:39 |
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Edit the Manuscript by Language Editor |
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2022-04-11 10:51 |
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Typeset the Manuscript |
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2022-06-01 13:09 |
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Publish the Manuscript Online |
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2022-06-17 03:19 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Development of clustered regularly interspaced short palindromic repeats/CRISPR-associated technology for potential clinical applications
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yue-Ying Huang, Xiao-Yu Zhang, Ping Zhu and Ling Ji |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shenzhen Science and Technology R&D Fund |
JCYJ20190809095203586 |
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| Corresponding Author |
Ling Ji, Doctor, Chief Technician, Department of Laboratory Medicine, Peking University Shenzhen Hospital, No. 1120 Lianhua Road , Futian District, Shenzhen 518035, Guangdong Province, China. 1120303921@qq.com |
| Key Words |
CRISPR-Cas; Gene editing; Molecular diagnostics; Gene targeting |
| Core Tip |
This review mainly discusses and explores the potential clinical applications of the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) technology. The detection technologies for nucleic acids and small molecules of different pathogens based on the CRISPR/Cas system are summarized. The advantages and disadvantages of the CRISPR/Cas technology from the aspects of gene editing, disease treatment, multi-drug resistance, and treatment are enumerated, asserting that CRISPR/Cas system has unlimited potential in clinical applications with certain challenges. |
| Publish Date |
2022-06-17 03:19 |
| Citation |
Huang YY, Zhang XY, Zhu P, Ji L. Development of clustered regularly interspaced short palindromic repeats/CRISPR-associated technology for potential clinical applications. World J Clin Cases 2022; 10(18): 5934-5945
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| URL |
https://www.wjgnet.com/2307-8960/full/v10/i18/5934.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i18.5934 |
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