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Articles Published Processes
5/12/2022 8:42:29 AM | Browse: 298 | Download: 578
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Received |
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2021-12-07 04:59 |
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Peer-Review Started |
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2021-12-07 05:00 |
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To Make the First Decision |
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Return for Revision |
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2022-01-27 07:58 |
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Revised |
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2022-02-01 01:08 |
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Second Decision |
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2022-03-22 06:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-03-27 05:25 |
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Articles in Press |
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2022-03-27 05:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-03-18 03:02 |
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Typeset the Manuscript |
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2022-05-04 04:18 |
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Publish the Manuscript Online |
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2022-05-12 08:42 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Basic Study |
| Article Title |
Gut mucosal microbiota profiles linked to colorectal cancer recurrence
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rui-Xue Huo, Yi-Jia Wang, Shao-Bin Hou, Wei Wang, Chun-Ze Zhang and Xue-Hua Wan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Tianjin Science and Technology Plan Project |
19YFZCSY00170 |
| Tianjin Union Medical Center |
2019YJ007 |
| Beijing Medical and Health Foundation |
F1814B |
| Key R&D Projects in the Tianjin Science and Technology Pillar Program |
19YFZCSY00420 |
| National Key R&D Program of China |
2017YFC1700606 |
| National Key R&D Program of China |
2017YFC1700604 |
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| Corresponding Author |
Xue-Hua Wan, PhD, Assistant Professor, Senior Researcher, TEDA Institute of Biological Sciences and Biotechnology, Nankai University, No. 23 Hongda Street, Tianjin 300457, China. xuehua.wan@nankai.edu.cn |
| Key Words |
Gut microbiota; Colorectal cancer; Prognosis; Colorectal cancer recurrence; Biomarker; 16S rRNA sequencing analysis |
| Core Tip |
Emerging evidence indicates that besides genetic and epigenetic factors, the gut microbiota is capable of driving colorectal cancer (CRC) progression. Here, we analyzed the gut mucosal microbiota of 75 triplet-paired samples collected from on-tumor, adjacent-tumor and off-tumor sites of patients diagnosed with/without CRC recurrence and 26 healthy controls. After a long-term follow-up, we identified spatial-specific bacterial taxa whose abundances are associated with overall survival and disease-free survival. Our data reveal the profiles of gut mucosal microbiota that increase risk of CRC recurrence and affect patient prognosis, which may serve as potential new biomarkers for CRC diagnosis. |
| Publish Date |
2022-05-12 08:42 |
| Citation |
Huo RX, Wang YJ, Hou SB, Wang W, Zhang CZ, Wan XH. Gut mucosal microbiota profiles linked to colorectal cancer recurrence. World J Gastroenterol 2022; 28(18): 1946-1964 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i18/1946.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i18.1946 |
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