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Articles Published Processes
7/18/2022 9:47:46 AM | Browse: 310 | Download: 912
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Received |
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2021-11-07 14:22 |
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Peer-Review Started |
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2021-11-07 14:23 |
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To Make the First Decision |
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Return for Revision |
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2021-12-12 05:39 |
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Revised |
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2021-12-25 07:07 |
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Second Decision |
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2022-06-24 03:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-06-24 22:09 |
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Articles in Press |
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2022-06-24 22:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-06-19 21:50 |
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Typeset the Manuscript |
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2022-07-07 09:19 |
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Publish the Manuscript Online |
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2022-07-18 09:47 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Letter to the Editor |
Article Title |
Hepatitis B core-related antigen: Are we near a treatment endpoint?
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Tarana Gupta |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Tarana Gupta, Doctor, MBBS, MD, Professor, Medicine, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, House No. 1065 A Sector 1, Rohtak 124001, Haryana, India. taranagupta@gmail.com |
Key Words |
Hepatitis B core-related antigen; Chronic hepatitis B; Covalently closed circular DNA; Hepatitis B e antigen seroconversion; Hepatitis B virus DNA; Pregenomic RNA |
Core Tip |
This study highlights the predictive role of hepatitis B core-related antigen (HBcrAg) levels at baseline, and after 24 and 48 wk of antiviral therapy for hepatitis B e antigen seroconversion in chronic hepatitis B patients. The issues related to poor sensitivity of assays and detectable levels in hepatitis B surface antigen-negative patients are major concerns. Future research on the utility of HBcrAg in hepatitis B virus (HBV) flare after nucleotide cessation, occult HBV reactivation, and risk of developing hepatocellular carcinoma is also needed. |
Publish Date |
2022-07-18 09:47 |
Citation |
Gupta T. Hepatitis B core-related antigen: Are we near a treatment endpoint? World J Gastroenterol 2022; 28(27): 3532-3534 |
URL |
https://www.wjgnet.com/1007-9327/full/v28/i27/3532.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v28.i27.3532 |
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