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4/6/2022 8:50:05 AM | Browse: 344 | Download: 655
Publication Name World Journal of Gastroenterology
Manuscript ID 73077
Country/Territory China
Received
2021-11-09 04:06
Peer-Review Started
2021-11-09 04:08
To Make the First Decision
Return for Revision
2022-01-09 08:25
Revised
2022-01-22 04:25
Second Decision
2022-03-04 05:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-03-06 22:53
Articles in Press
2022-03-06 22:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-03-30 07:59
Publish the Manuscript Online
2022-04-06 08:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Radiomics signature: A potential biomarker for β-arrestin1 phosphorylation prediction in hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Feng Che, Qing Xu, Qian Li, Zi-Xing Huang, Cai-Wei Yang, Li-Ye Wang, Yi Wei, Yu-Jun Shi and Bin Song
ORCID
Author(s) ORCID Number
Feng Che http://orcid.org/0000-0002-8008-2696
Qing Xu http://orcid.org/0000-0001-9438-5535
Qian Li http://orcid.org/0000-0001-8330-7654
Zi-Xing Huang http://orcid.org/0000-0001-7967-5948
Cai-Wei Yang http://orcid.org/0000-0003-3335-3948
Li-Ye Wang http://orcid.org/0000-0002-5535-4514
Yi Wei http://orcid.org/0000-0003-3993-9747
Yu-Jun Shi http://orcid.org/0000-0003-0494-6023
Bin Song http://orcid.org/0000-0002-7269-2101
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81971571
Science and Technology Support Program of Sichuan Province 2021YFS0144
Science and Technology Support Program of Sichuan Province 2021YFS0021
China Postdoctoral Science Foundation 2021M692289
Corresponding Author Bin Song, MD, Chief Doctor, Doctor, Professor, Department of Radiology, West China Hospital, Sichuan University, No 37, GUOXUE Alley, Wuhou district, Chengdu 610041, China. songlab_radiology@163.com
Key Words Hepatocellular carcinoma; Sorafenib resistance; β-Arrestin1 phosphorylation; Radiomics; Computed tomography; Overall survival
Core Tip The aim of this study was to develop and validate radiomics-based models for predicting β-arrestin1 phosphorylation in hepatocellular carcinoma (HCC). A total of 99 HCC patients (training cohort: n = 69; validation cohort: n = 30) were included, and the final clinico-radiological-radiomics model integrating the radiomics scores and clinico-radiological risk factors showed satisfactory discriminative performance (AUC = 0.898, 95%CI, 0.820 to 0.977). The preoperative prediction model can be used as a noninvasive and effective tool to help predict the outcome of HCC patients treated with sorafenib and identify patients who would benefit most from sorafenib treatment.
Publish Date 2022-04-06 08:50
Citation Che F, Xu Q, Li Q, Huang ZX, Yang CW, Wang LY, Wei Y, Shi YJ, Song B. Radiomics signature: A potential biomarker for β-arrestin1 phosphorylation prediction in hepatocellular carcinoma. World J Gastroenterol 2022; 28(14): 1479-1493
URL https://www.wjgnet.com/1007-9327/full/v28/i14/1479.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i14.1479
Full Article (PDF) WJG-28-1479.pdf
Full Article (Word) WJG-28-1479.docx
Manuscript File 73077_Auto_Edited.docx
Answering Reviewers 73077-Biostatistics statement.pdf
Audio Core Tip 73077-Audio core tip.m4a
Biostatistics Review Certificate 73077-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 73077-Conflict-of-interest statement.pdf
Copyright License Agreement 73077-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 73077-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 73077-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 73077-Language certificate.pdf
Peer-review Report 73077-Peer-review(s).pdf
Scientific Misconduct Check 73077-Bing-Wu YXJ-2.png
Scientific Editor Work List 73077-Scientific editor work list.pdf