4/6/2022 8:50:05 AM | Browse: 498 | Download: 1021
| Publication Name | World Journal of Gastroenterology |
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| Manuscript ID | 73077 |
| Country | China |
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| ISSN | 1007-9327 (print) and 2219-2840 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright | ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Gastroenterology & Hepatology | ||||||||||||||||||||
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| Manuscript Type | Retrospective Study | ||||||||||||||||||||
| Article Title | Radiomics signature: A potential biomarker for β-arrestin1 phosphorylation prediction in hepatocellular carcinoma | ||||||||||||||||||||
| Manuscript Source | Invited Manuscript | ||||||||||||||||||||
| All Author List | Feng Che, Qing Xu, Qian Li, Zi-Xing Huang, Cai-Wei Yang, Li-Ye Wang, Yi Wei, Yu-Jun Shi and Bin Song | ||||||||||||||||||||
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| Corresponding Author | Bin Song, MD, Chief Doctor, Doctor, Doctor, Professor, Department of Radiology, West China Hospital, Sichuan University, No 37, GUOXUE Alley, Wuhou district, Chengdu 610041, Sichuan Province, China. songlab_radiology@163.com | ||||||||||||||||||||
| Key Words | Hepatocellular carcinoma; Sorafenib resistance; β-Arrestin1 phosphorylation; Radiomics; Computed tomography; Overall survival | ||||||||||||||||||||
| Core Tip | The aim of this study was to develop and validate radiomics-based models for predicting β-arrestin1 phosphorylation in hepatocellular carcinoma (HCC). A total of 99 HCC patients (training cohort: n = 69; validation cohort: n = 30) were included, and the final clinico-radiological-radiomics model integrating the radiomics scores and clinico-radiological risk factors showed satisfactory discriminative performance (AUC = 0.898, 95%CI, 0.820 to 0.977). The preoperative prediction model can be used as a noninvasive and effective tool to help predict the outcome of HCC patients treated with sorafenib and identify patients who would benefit most from sorafenib treatment. | ||||||||||||||||||||
| Publish Date | 2022-04-06 08:50 | ||||||||||||||||||||
| Citation | Che F, Xu Q, Li Q, Huang ZX, Yang CW, Wang LY, Wei Y, Shi YJ, Song B. Radiomics signature: A potential biomarker for β-arrestin1 phosphorylation prediction in hepatocellular carcinoma. World J Gastroenterol 2022; 28(14): 1479-1493 | ||||||||||||||||||||
| URL | https://www.wjgnet.com/1007-9327/full/v28/i14/1479.htm | ||||||||||||||||||||
| DOI | https://dx.doi.org/10.3748/wjg.v28.i14.1479 |
| Full Article (PDF) | WJG-28-1479.pdf |
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| Full Article (Word) | WJG-28-1479.docx |
| Manuscript File | 73077_Auto_Edited.docx |
| Answering Reviewers | 73077-Biostatistics statement.pdf |
| Audio Core Tip | 73077-Audio core tip.m4a |
| Biostatistics Review Certificate | 73077-Biostatistics statement.pdf |
| Conflict-of-Interest Disclosure Form | 73077-Conflict-of-interest statement.pdf |
| Copyright License Agreement | 73077-Copyright license agreement.pdf |
| Signed Informed Consent Form(s) or Document(s) | 73077-Informed consent statement.pdf |
| Institutional Review Board Approval Form or Document | 73077-Institutional review board statement.pdf |
| Non-Native Speakers of English Editing Certificate | 73077-Language certificate.pdf |
| Peer-review Report | 73077-Peer-review(s).pdf |
| Scientific Misconduct Check | 73077-Bing-Wu YXJ-2.png |
| Scientific Editor Work List | 73077-Scientific editor work list.pdf |
| CrossCheck Report | 73077-CrossCheck report.pdf |