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Articles Published Processes
7/13/2022 1:27:24 AM | Browse: 711 | Download: 2075
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Received |
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2021-11-18 09:42 |
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Peer-Review Started |
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2021-11-18 09:44 |
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First Decision by Editorial Office Director |
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2022-01-12 06:55 |
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Return for Revision |
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2022-01-12 06:55 |
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Revised |
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2022-01-26 15:31 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-03-23 06:21 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-03-27 06:59 |
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Articles in Press |
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2022-03-27 06:59 |
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Edit the Manuscript by Language Editor |
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2022-05-31 16:49 |
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Typeset the Manuscript |
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2022-07-07 06:44 |
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Publish the Manuscript Online |
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2022-07-13 01:27 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
KIFC3 promotes proliferation, migration, and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Weiwei Hao and Feng Xu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Feng Xu, MD, Chief Doctor, Professor, Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University, No.01 Jianshe East Road, Zhengzhou, China, Zhengzhou 450052, Henan Province, China. xufengmd@sina.com |
| Key Words |
Esophageal squamous cell carcinoma; KIFC3; β-catenin; Proliferation; Migration; Invasion |
| Core Tip |
Esophageal squamous cell carcinoma (ESCC) is one of the most dangerous malignancies affecting human health. However, the mechanism of ESCC is still unclear. Here, our study reveals that KIFC3 is upregulated in ESCC. In addition, overexpressed KIFC3 is associated with poor prognosis in ESCC patients. Furthermore, in vitro and in vivo experiments reveal that KIFC3 promotes the proliferation, migration, and invasion of ESCC cells by activating EMT and β-catenin signaling. Our study strongly suggests that KIFC3 may be a potential new therapeutic target for ESCC treatment. |
| Publish Date |
2022-07-13 01:27 |
| Citation |
Hao WW, Xu F. KIFC3 promotes proliferation, migration, and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling. World J Gastrointest Oncol 2022; 14(7): 1239-1251
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| URL |
https://www.wjgnet.com/1948-5204/full/v14/i7/1239.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i7.1239 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
