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Articles Published Processes
8/25/2014 5:12:00 PM | Browse: 935 | Download: 905
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Received |
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2013-11-14 07:48 |
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Peer-Review Started |
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2013-11-14 16:38 |
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To Make the First Decision |
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2013-12-26 10:45 |
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Return for Revision |
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2013-12-27 11:10 |
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Revised |
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2014-01-10 19:42 |
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Second Decision |
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2014-05-14 09:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-05-14 09:40 |
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Articles in Press |
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2014-05-23 09:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-06-30 16:01 |
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Publish the Manuscript Online |
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2014-07-21 17:17 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Non-alcoholic fatty liver disease and type 2 diabetes mellitus: The liver disease of our age?
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Manuscript Source |
Invited Manuscript |
All Author List |
Gábor Firneisz |
Funding Agency and Grant Number |
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Corresponding Author |
Gábor Firneisz, MD, PhD, 2nd Department of Internal Medicine, Semmelweis University, Szentkiralyi St 46, H-1088 Budapest, Hungary. firneisz.gabor@med.semmelweis-univ.hu |
Key Words |
Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Liver cirrhosis; Hepatocellular cancer; Dysfunctional adipose tissue; Type 2 diabetes mellitus; Insulin resistance; Obesity; Genetics; Therapy |
Core Tip |
In this review article, non-alcoholic fatty liver disease (NAFLD) spectrum disease is discussed in detail. The epidemiology of NAFLD/nonalcoholic steatohepatitis and the relationship of NAFLD to different forms of diabetes mellitus including type 2 diabetes mellitus and gestational diabetes mellitus are reviewed. Attention is paid to the main biochemical events, to dysfunctional adipose tissue and visceral adiposity associated with NAFLD and insulin resistance, to mitochondrial dysfunction and to the role of the entero-insular axis in NAFLD. Genetics and potential pharmacological approaches are discussed. |
Publish Date |
2014-07-21 17:17 |
Citation |
Firneisz G. Non-alcoholic fatty liver disease and type 2 diabetes mellitus: The liver disease of our age? World J Gastroenterol 2014; 20(27): 9072-9089 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i27/9072.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i27.9072 |
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