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5/17/2022 2:00:49 AM | Browse: 748 | Download: 1833
Publication Name World Journal of Experimental Medicine
Manuscript ID 73448
Country India
Received
2021-11-21 18:53
Peer-Review Started
2021-11-21 18:57
First Decision by Editorial Office Director
2022-01-12 09:01
Return for Revision
2022-01-12 09:01
Revised
2022-01-24 05:43
Publication Fee Transferred
Second Decision by Editor
2022-04-12 01:58
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2022-04-21 19:31
Articles in Press
2022-04-21 19:31
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-04-26 08:43
Publish the Manuscript Online
2022-05-17 02:00
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Minireviews
Article Title Use of hydroxychloroquine and azithromycin combination to treat the COVID-19 infection
Manuscript Source Invited Manuscript
All Author List Jyoti bajpai, Akshyaya Pradhan, Ajay Kumar Verma and Surya Kant
ORCID
Author(s) ORCID Number
Jyoti bajpai http://orcid.org/0000-0001-6337-856X
Akshyaya Pradhan http://orcid.org/0000-0002-2360-7580
Ajay Kumar Verma http://orcid.org/0000-0002-2973-1793
Surya Kant http://orcid.org/0000-0001-7520-5404
Funding Agency and Grant Number
Corresponding Author Surya Kant, FCCP, Professor, Department of Pulmonary Medicine, King George Medical University, Department of Pulmonary Medicine, King George Medical University, Lucknow, India. Electronic address: skantpulmed@gmail.com., lucknow 226003, uttar pradesh, India. skantpulmed@gmail.com
Key Words Hydroxychloroquine; Azithromycin; Antiviral effects; QT interval; Randomized controlled trial
Core Tip The coronavirus disease 2019 (COVID-19) pandemic has raged across the globe imposing a huge burden on the health systems. In absence of definitive treatment or vaccines, many drugs with antiviral properties were repurposed for use against COVID-19 infection. Based on the results of preliminary success in observational studies, Hydroxychloroquine (HCQS) and azithromycin were used extensively in the initial part of pandemic in he management of COVID-19 pandemic. Subsequently, reports of QT prolongation emerged with HCQS and its combination therapy with azithromycin. Later on HCQS was discontinued by major guidelines including World Health Organization. The review traces the emergence and downfall of the combination therapy in management of COVID-19.
Publish Date 2022-05-17 02:00
Citation Bajpai J, Pradhan A, Verma AK, Kant S. Use of hydroxychloroquine and azithromycin combination to treat the COVID-19 infection. World J Exp Med 2022; 12(3): 44-52
URL https://www.wjgnet.com/2220-315x/full/v12/i3/44.htm
DOI https://dx.doi.org/10.5493/wjem.v12.i3.44
Full Article (PDF) WJEM-12-44.pdf
Full Article (Word) WJEM-12-44.docx