Publication Name	World Journal of Clinical Cases
Manuscript ID	73474
Country	China

Received	2021-11-27 07:20
Peer-Review Started	2021-11-27 07:23
To Make the First Decision
Return for Revision	2022-01-12 01:06
Revised	2022-01-22 16:39
Second Decision	2022-05-30 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-06-03 21:20
Articles in Press	2022-06-03 21:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-06-30 13:06
Publish the Manuscript Online	2022-07-11 08:36

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Programmed cell death-1 inhibitor combination treatment for recurrent proficient mismatch repair/ miscrosatellite-stable type endometrial cancer: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Chong-Ya Zhai, Lu-Xi Yin and Wei-Dong Han
ORCID	Author(s) ORCID Number Chong-Ya Zhai http://orcid.org/0000-0002-3291-1066 Lu-Xi Yin http://orcid.org/0000-0002-8181-5353 Wei-Dong Han http://orcid.org/0000-0001-7227-3671
Funding Agency and Grant Number	Funding Agency Grant Number Hangzhou Health and Family Planning and Science and Technology Program OO20190347
Corresponding Author	Wei-Dong Han, MD, Chief Doctor, Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310020, Zhejiang Province, China. hanwd@zju.edu.cn
Key Words	Refractory endometrial cancer; Proficient mismatch repair; Miscrosatellite-stable; Immunotherapy; Case report
Core Tip	Endometrial cancer (EC) with proficient mismatch repair/miscrosatellite-stable (pMMR/MSS)-type hardly responds to immune checkpoint therapy. This case reported a satisfactory outcome with well-tolerated toxicities using toripalimab combined with anlotinib treatment in an EC patient with pMMR/MSS-type. Although need further clinical evidence, programmed cell death-1 inhibitor combined anti-angiogenesis therapy may present an option for EC patients with pMMR/MSS-type after multi-line treatment.
Publish Date	2022-07-11 08:36
Citation	Zhai CY, Yin LX, Han WD. Programmed cell death-1 inhibitor combination treatment for recurrent proficient mismatch repair/ miscrosatellite-stable type endometrial cancer: A case report. World J Clin Cases 2022; 10(21): 7474-7482
URL	https://www.wjgnet.com/2307-8960/full/v10/i21/7474.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i21.7474

Full Article (PDF)	WJCC-10-7474.pdf
Full Article (Word)	WJCC-10-7474.docx
CARE Checklist–2016	73474-CARE-Checklist–2016-revision.pdf
Manuscript File	73474_Auto_Edited-LS.docx
Answering Reviewers	73474-Answering reviewers.pdf
Audio Core Tip	73474-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	73474-Conflict-of-interest statement.pdf
Copyright License Agreement	73474-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	73474-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	73474-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	73474-Language certificate.pdf
Journal Editor-in-Chief Review Report	73474-Peer-review(s).pdf
Scientific Misconduct Check	73474-Bing-Chen YL-2.png
Scientific Editor Work List	73474-Scientific editor work list.pdf
CrossCheck Report	73474-CrossCheck report.pdf