Publication Name	World Journal of Clinical Cases
Manuscript ID	73735
Country	Czech Republic

Received	2021-12-02 07:12
Peer-Review Started	2021-12-02 07:14
To Make the First Decision
Return for Revision	2022-01-09 20:22
Revised	2022-01-22 14:38
Second Decision	2022-03-25 06:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-03-26 21:35
Articles in Press	2022-03-26 21:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-28 07:04
Publish the Manuscript Online	2022-05-24 14:32

ISSN	2307-8960 (online)
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Category	Surgery
Manuscript Type	Case Report
Article Title	Spontaneous liver rupture following SARS-CoV-2 infection in late pregnancy: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Radek Ambrož, Martin Stašek, Ján Molnár, Petr Špička, Dušan Klos, Jozef Hambálek and Daniela Skanderová
ORCID	Author(s) ORCID Number Radek Ambrož http://orcid.org/0000-0002-5572-3148 Martin Stašek http://orcid.org/0000-0002-1308-7390 Ján Molnár http://orcid.org/0000-0002-4231-1726 Petr Špička http://orcid.org/0000-0003-3166-2624 Dušan Klos http://orcid.org/0000-0002-3097-4418 Jozef Hambálek http://orcid.org/0000-0003-3047-674X Daniela Skanderová http://orcid.org/0000-0001-9106-8104
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Health, Czech Republic-conceptual Development of Research Organization No. FNOl 00098892
Corresponding Author	Martin Stašek, MD, PhD, Surgeon, Department of Surgery I, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University, 92/13 I.P. Pavlova, Nová Ulice, Olomouc 77900, Czech Republic. martin.stasek@fnol.cz
Key Words	Liver rupture; SARS-CoV-2; Pregnancy; Abortion; HELLP; Case report
Core Tip	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may contribute to the worsening of hepatopathy during pregnancy, because of its effect on the endothelium in the systemic inflammatory response syndrome microenvironment. Liver rupture causes high mortality in both the mother and fetus. Such a life-threatening scenario requires close collaboration between the obstetrician and the surgeon with an urgent indication for cesarean section, preferably by midline laparotomy with meticulous control of the liver and treatment of any injury. The presence of SARS-CoV-2 in pregnant women and its association with the development of severe hepatopathy in pregnancy requires further research.
Publish Date	2022-05-24 14:32
Citation	Ambrož R, Stašek M, Molnár J, Špička P, Klos D, Hambálek J, Skanderová D. Spontaneous liver rupture following SARS-CoV-2 infection in late pregnancy: A case report. World J Clin Cases 2022; 10(15): 5042-5050
URL	https://www.wjgnet.com/2307-8960/full/v10/i15/5042.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i15.5042

Full Article (PDF)	WJCC-10-5042.pdf
Full Article (Word)	WJCC-10-5042.docx
CARE Checklist–2016	73735-CARE-Checklist–2016-revision.pdf
Manuscript File	73735_Auto_Edited.docx
Answering Reviewers	73735-Answering reviewers.pdf
Audio Core Tip	73735-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	73735-Conflict-of-interest statement.pdf
Copyright License Agreement	73735-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	73735-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	73735-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	73735-Language certificate.pdf
Peer-review Report	73735-Peer-review(s).pdf
Scientific Misconduct Check	73735-Bing-Chen YL-2.png
Scientific Editor Work List	73735-Scientific editor work list.pdf
CrossCheck Report	73735-CrossCheck report.pdf