Publication Name	World Journal of Gastroenterology
Manuscript ID	7377
Country	Italy

Received	2013-11-15 15:44
Peer-Review Started	2013-11-19 09:11
To Make the First Decision	2013-12-26 10:44
Return for Revision	2013-12-26 17:18
Revised	2014-01-09 23:37
Second Decision	2014-01-20 17:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-20 18:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-25 09:07
Publish the Manuscript Online	2014-04-29 09:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Adjuvant chemotherapy for gastric cancer: Current evidence and future challenges
Manuscript Source	Invited Manuscript
All Author List	Rosalba Miceli, Gianluca Tomasello, Giacomo Bregni, Maria Di Bartolomeo and Filippo Pietrantonio
Funding Agency and Grant Number
Corresponding Author	Rosalba Miceli, PhD, Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milan, Italy. rosalba.miceli@istitutotumori.mi.it
Key Words	Gastric cancer; Adjuvant chemotherapy; Radiotherapy; Randomized trial
Core Tip	Despite the benefit of adjuvant therapy has been clearly demonstrated, no general consensus has been still reached on the best treatment option. The narrow therapeutic index of adjuvant chemotherapy requires a careful assessment of expected risks and benefits for individual patients. Many issues, such as the role of postoperative radiotherapy and the best chemotherapy regimen, are still under investigation. Moreover, no prognostic or predictive factors beyond pathological stage have been prospectively validated. Despite researchers’ efforts, this issue still represent an unmet medical need. In this review we describe the recently completed landmark studies and meta analyses, and we discuss the future challenges in this research field.
Publish Date	2014-04-29 09:53
Citation	Miceli R, Tomasello G, Bregni G, Di Bartolomeo M, Pietrantonio F. Adjuvant chemotherapy for gastric cancer: Current evidence and future challenges. World J Gastroenterol 2014; 20(16): 4516-4525
URL	http://www.wjgnet.com/1007-9327/full/v20/i16/4516.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i16.4516

Full Article (PDF)	WJG-20-4516.pdf
Full Article (Word)	WJG-20-4516.doc
Manuscript File	7377-Review.docx
Answering Reviewers	7377-Answering reviewers.pdf
Copyright License Agreement	7377-Copyright assignment.pdf
Peer-review Report	7377-Peer reviews.pdf
Scientific Editor Work List	7377-Scientific editor work list.doc