Publication Name	World Journal of Gastroenterology
Manuscript ID	73906
Country	United States

Received	2021-12-10 21:33
Peer-Review Started	2021-12-10 21:36
To Make the First Decision
Return for Revision	2022-01-08 07:57
Revised	2022-01-18 02:40
Second Decision	2022-04-21 02:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-04-25 16:35
Articles in Press	2022-04-25 16:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-05-20 08:20
Publish the Manuscript Online	2022-06-02 12:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Endoscopic ultrasound-guided injectable therapy for pancreatic cancer: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Jyotroop Kaur, Veeravich Jaruvongvanich and Vinay Chandrasekhara
ORCID	Author(s) ORCID Number Jyotroop Kaur http://orcid.org/0000-0002-5085-9265 Veeravich Jaruvongvanich http://orcid.org/0000-0002-3419-2296 Vinay Chandrasekhara http://orcid.org/0000-0001-6209-9905
Funding Agency and Grant Number
Corresponding Author	Vinay Chandrasekhara, FASGE, MD, Associate Professor, Attending Doctor, Department of Gastroenterology and Hepatology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, United States. chandrasekhara.vinay@mayo.edu
Key Words	Pancreatic ductal adenocarcinoma; Endoscopic ultrasound-guided fine-needle injection; Local injectable therapy; Immunotherapy; Chemotherapy; Oncolytic viral therapy
Core Tip	Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy. Resistance to systemic therapies may be attributable to the dense stromal matrix in the pancreatic tumor mass. Endoscopic ultrasound-guided fine-needle injection (EUS-FNI) is a novel technique to deliver various anti-tumor agents locally in real-time and may overcome this limitation. This review examines the EUS-FNI therapies used to treat PDAC.
Publish Date	2022-06-02 12:11
Citation	Kaur J, Jaruvongvanich V, Chandrasekhara V. Endoscopic ultrasound-guided injectable therapy for pancreatic cancer: A systematic review. World J Gastroenterol 2022; 28(21): 2383-2395
URL	https://www.wjgnet.com/1007-9327/full/v28/i21/2383.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i21.2383

Full Article (PDF)	WJG-28-2383.pdf
Full Article (Word)	WJG-28-2383.docx
Manuscript File	73906_Auto_Edited_LM.docx
Answering Reviewers	73906-Answering reviewers.pdf
Audio Core Tip	73906-Audio core tip.aac
Biostatistics Review Certificate	73906-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	73906-Conflict-of-interest statement.pdf
Copyright License Agreement	73906-Copyright license agreement.pdf
Supplementary Material	73906-Supplementary material.pdf
Peer-review Report	73906-Peer-review(s).pdf
Scientific Misconduct Check	73906-Bing-Chen YL-2.png
Scientific Editor Work List	73906-Scientific editor work list.pdf
CrossCheck Report	73906-CrossCheck report.pdf