| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Retrospective Study |
| Article Title |
Contrast-enhanced ultrasound Liver Imaging Reporting and Data System: Lights and shadows in hepatocellular carcinoma and cholangiocellular carcinoma diagnosis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Gianpaolo Vidili, Marco Arru, Giuliana Solinas, Diego Francesco Calvisi, Pierluigi Meloni, Assunta Sauchella, Davide Turilli, Claudio Fabio, Antonio Cossu, Giordano Madeddu, Sergio Babudieri, Maria Assunta Zocco, Giovanni Iannetti, Enza Di Lembo, Alessandro Palmerio Delitala and Roberto Manetti |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fondazione di Sardegna |
No. FDS2019VIDILI |
|
| Corresponding Author |
Gianpaolo Vidili, MD, Assistant Professor, Department of Medical, Surgical and Experimental Sciences, University of Sassari, 8 Viale San Pietro, Sassari 07100, Italy. gianpaolovidili@uniss.it |
| Key Words |
Contrast-enhanced ultrasound Liver Imaging Reporting and Data System; Hepatocellular carcinoma; Intrahepatic cholangiocarcinoma; Cirrhosis; Contrast-enhanced ultrasound; Liver |
| Core Tip |
This is a retrospective study to evaluate the accuracy of contrast-enhanced ultrasound Liver Imaging Reporting and Data System (CEUS LI-RADS) in correctly diagnosing hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) in patients with cirrhosis. CEUS LR-5 showed a 97.7% specificity for HCC with a low sensitivity (67.6%), while the CEUS LR-4 and 5 merged class showed a 93.9% sensitivity and 94.3% specificity for HCC. CEUS LR-M predicted ICC with a 91.3% sensitivity and 96.7% specificity. CEUS LR-3 predominantly included benign lesions (28.8% of malignancies) but was heterogeneous as the hypo-hypo pattern showed a higher rate of malignant lesions (73.3%) than the iso-iso pattern (2.6%). |
| Publish Date |
2022-07-18 09:47 |
| Citation |
Vidili G, Arru M, Solinas G, Calvisi DF, Meloni P, Sauchella A, Turilli D, Fabio C, Cossu A, Madeddu G, Babudieri S, Zocco MA, Iannetti G, Di Lembo E, Delitala AP, Manetti R. Contrast-enhanced ultrasound Liver Imaging Reporting and Data System: Lights and shadows in hepatocellular carcinoma and cholangiocellular carcinoma diagnosis. World J Gastroenterol 2022; 28(27): 3488-3502 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i27/3488.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i27.3488 |
