Publication Name	World Journal of Psychiatry
Manuscript ID	74162
Country	United States

Received	2021-12-31 11:02
Peer-Review Started	2021-12-31 11:04
To Make the First Decision
Return for Revision	2022-03-13 21:25
Revised	2022-04-03 14:44
Second Decision	2022-05-18 03:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-05-23 01:04
Articles in Press	2022-05-23 01:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-05-27 01:26
Publish the Manuscript Online	2022-06-14 07:57

ISSN	2220-3206 (online)
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Category	Psychiatry
Manuscript Type	Observational Study
Article Title	Disrupted leptin-fatty acid biosynthesis is an early manifestation of metabolic abnormalities in schizophrenia
Manuscript Source	Invited Manuscript
All Author List	Mohammad M Khan
ORCID	Author(s) ORCID Number Mohammad M Khan http://orcid.org/0000-0001-5973-447X
Funding Agency and Grant Number
Corresponding Author	Mohammad M Khan, PhD, Professor, Laboratory of Translational Neurology and Molecular Psychiatry, Department of Biotechnology, Era's Lucknow Medical College and Hospital, and Faculty of Science, Era University, Sarfarazganj, Hardoi Road, Lucknow 226003, India. mmkhan0@gmail.com
Key Words	Schizophrenia; Leptin; Fatty acids; Insulin resistance; Impaired energy expenditure
Core Tip	Insulin resistance (IR) and impaired energy expenditure (IEE) are untreatable metabolic comorbidities in schizophrenia. Leptin and fatty acids have profound influence on insulin synthesis, secretion and energy metabolism. Although previous studies have measured plasma leptin and membrane fatty acids in schizophrenia, findings are very heterogeneous, and moreover, no single study has ever measured both plasma leptin and membrane fatty acids together in the same cohort of schizophrenia patients. These studies are crucial not only for analyzing the relationship between leptin and fatty acids in the same cohort of schizophrenia patients, but also for deciphering their role in the development of IR and IEE.
Publish Date	2022-06-14 07:57
Citation	Khan MM. Disrupted leptin-fatty acid biosynthesis is an early manifestation of metabolic abnormalities in schizophrenia. World J Psychiatry 2022; 12(6): 827-842
URL	https://www.wjgnet.com/2220-3206/full/v12/i6/827.htm
DOI	https://dx.doi.org/10.5498/wjp.v12.i6.827

Full Article (PDF)	WJP-12-827.pdf
Full Article (Word)	WJP-12-827.docx
Manuscript File	74162_Auto_Edited-LS.docx
Answering Reviewers	74162-Answering reviewers.pdf
Audio Core Tip	74162-Audio core tip.m4a
Biostatistics Review Certificate	74162-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	74162-Conflict-of-interest statement.pdf
Copyright License Agreement	74162-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document	74162-Institutional review board statement.pdf
Peer-review Report	74162-Peer-review(s).pdf
Scientific Editor Work List	74162-Scientific editor work list.pdf
CrossCheck Report	74162-CrossCheck report.pdf