Publication Name	World Journal of Gastroenterology
Manuscript ID	7451
Country	Spain

Received	2013-11-19 14:53
Peer-Review Started
To Make the First Decision
Return for Revision
Revised
Second Decision	2013-11-20 11:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-21 05:54
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-06 09:49
Publish the Manuscript Online	2014-01-14 20:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Liver transplantation for hilar cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Ricardo Robles, Francisco Sánchez-Bueno, Pablo Ramírez, Roberto Brusadin and Pascual Parrilla
Funding Agency and Grant Number
Corresponding Author	Ricardo Robles, Professor of Surgery and Head of Unit, Department of Surgery and Liver and Pancreas transplantation, Virgen de la Arrixaca Clinic and University Hospital, Ctra del Palmar, E-30120 Murcia, Spain. rirocam@um.es
Key Words	Klatskin tumour; Cholangiocarcinoma; Liver transplantation; Liver surgery; Primary sclerosing cholangitis
Core Tip	The most appropriate treatment for Klatskin tumor (KT) with a curative intention is multimodal therapy based on achieving R0 resection combined with other types of neoadjuvant or adjuvant treatment. In irresectable non-disseminated KT patients, using liver transplantation without neoadjuvant treatment, the 5-year survival rate increase to 38%, reaching 50% survival in early stage. In selected cases, with liver transplantation and neoadjuvant treatment (chemotherapy and radiotherapy), the actuarial survival rate is 65% at 5 years and 59% at 10 years. In conclusion, correct staging, neoadjuvant treatment, living donor and priority on the LT waiting list may lead to improved results.
Publish Date	2014-01-14 20:11
Citation	Robles R, Sánchez-Bueno F, Ramírez P, Brusadin R, Parrilla P. Liver transplantation for hilar cholangiocarcinoma. World J Gastroenterol 2013; 19(48): 9209-9215
URL	http://www.wjgnet.com/1007-9327/full/v19/i48/9209.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i48.9209

Full Article (PDF)	WJG-19-9209.pdf
Manuscript File	7451-Review.docx
Answering Reviewers	7451-Answering reviewers.pdf
Copyright License Agreement	7451-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7451-Language certificate.pdf
Peer-review Report	7451-Peer reviews.pdf
Scientific Editor Work List	7451-Scientific editor work list.doc