| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Effectiveness and safety of chemotherapy for patients with malignant gastrointestinal obstruction: A Japanese population-based cohort study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Gota Fujisawa, Ryota Niikura, Takuya Kawahara, Tetsuro Honda, Kenkei Hasatani, Naohiro Yoshida, Tsutomu Nishida, Tetsuya Sumiyoshi, Shu Kiyotoki, Takashi Ikeya, Masahiro Arai, Yoku Hayakawa, Takashi Kawai and Mitsuhiro Fujishiro |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Tokyo Medical University Cancer Research Foundation |
2021 |
| KAKENHI Grants-in-Aid for Scientific Research |
20K08375 |
|
| Corresponding Author |
Ryota Niikura, MD, PhD, Adjunct Associate Professor, Doctor, Gastroenterological Endoscopy, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 1600023, Japan. rniikura@triton.ocn.ne.jp |
| Key Words |
Gastrointestinal cancer; Chemotherapy; Malignant gastrointestinal obstruction; Self-expandable metal stent; Palliative surgery |
| Core Tip |
The impacts of chemotherapy on patients with malignant gastrointestinal obstructions remain unclear and multicenter evidence is lacking. Does chemotherapy improve the duration of gastrointestinal patency (and thus overall survival) in such patients? This multicenter observational study revealed that the median patency duration in the chemotherapy group was longer than that in the best supportive care (BSC) group (9.7 vs 2.5 mo). Similarly, the median overall survival was longer in the chemotherapy than the BSC group (19.3 vs 5.4 mo, log-rank test, P < 0.01). |
| Publish Date |
2022-06-02 10:05 |
| Citation |
Fujisawa G, Niikura R, Kawahara T, Honda T, Hasatani K, Yoshida N, Nishida T, Sumiyoshi T, Kiyotoki S, Ikeya T, Arai M, Hayakawa Y, Kawai T, Fujishiro M. Effectiveness and safety of chemotherapy for patients with malignant gastrointestinal obstruction: A Japanese population-based cohort study. World J Clin Cases 2022; 10(16): 5253-5265 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i16/5253.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i16.5253 |
