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Articles Published Processes
8/16/2022 11:59:52 AM | Browse: 280 | Download: 525
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Received |
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2022-01-16 02:20 |
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Peer-Review Started |
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2022-01-16 02:22 |
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To Make the First Decision |
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Return for Revision |
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2022-05-10 00:10 |
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Revised |
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2022-05-21 05:23 |
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Second Decision |
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2022-07-22 07:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-07-25 00:48 |
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Articles in Press |
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2022-07-25 00:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-07-19 16:53 |
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Typeset the Manuscript |
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2022-07-29 01:10 |
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Publish the Manuscript Online |
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2022-08-16 11:59 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Insights into induction of the immune response by the hepatitis B vaccine
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Federico Alejandro Di Lello, Alfredo Pedro Martínez and Diego Martín Flichman |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Diego Martín Flichman, PhD, Adjunct Professor, Research Scientist, Microbiology, Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Síndrome de Inmunodeficiencia Adquirida, Paraguay 2155, Buenos Aires C1121ABG, Argentina. dflichman@ffyb.uba.ar |
| Key Words |
Hepatitis B virus; Vaccine; Immune response; Antibodies; Neutralizing |
| Core Tip |
Second-generation vaccines induce the production of anti-hepatitis B surface antibodies (anti-HBs). Anti-HBs levels ≥ 10 mIU/mL prevent against infection. More than 90% of immunized persons achieve protective anti-HBs levels 1 mo after completing the three-dose vaccination schedule. Although antibody titers significantly drop during the 1st years after vaccination, memory immunity is sufficient to prevent infection regardless of the antibody levels. In some specific settings showing lower immune response rates, schemes with larger or additional doses and novel vaccine formulations are recommended. |
| Publish Date |
2022-08-16 11:59 |
| Citation |
Di Lello FA, Martínez AP, Flichman DM. Insights into induction of the immune response by the hepatitis B vaccine. World J Gastroenterol 2022; 28(31): 4249-4262 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i31/4249.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i31.4249 |
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