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Articles Published Processes
7/13/2022 7:30:59 AM | Browse: 404 | Download: 909
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Received |
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2022-01-16 19:14 |
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Peer-Review Started |
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2022-01-16 19:15 |
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To Make the First Decision |
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Return for Revision |
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2022-03-08 18:43 |
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Revised |
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2022-03-21 14:26 |
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Second Decision |
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2022-05-20 03:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-05-22 23:09 |
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Articles in Press |
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2022-05-22 23:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-05-14 14:17 |
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Typeset the Manuscript |
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2022-06-22 07:19 |
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Publish the Manuscript Online |
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2022-07-13 07:30 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Role of baicalin as a potential therapeutic agent in hepatobiliary and gastrointestinal disorders: A review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Risha Ganguly, Ashutosh Gupta and Abhay K Pandey |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University Grants Commission, New Delhi, India in The Form of UGC-Junior and Senior Research Fellowships |
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| Corresponding Author |
Abhay K Pandey, PhD, Full Professor, Department of Biochemistry, University of Allahabad, Faculty of Science, Katra, Allahabad (Prayagraj) 211002, Uttar Pradesh, India. akpandey23@rediffmail.com |
| Key Words |
Baicalin; Biotransformation; Gut microbiota; Hepatobiliary and gastrointestinal disorders; Signaling pathways |
| Core Tip |
Baicalin possesses therapeutic efficacy against hepatic and gastrointestinal diseases including hepatic fibrosis, xenobiotic induced liver injury, fatty liver disease, viral hepatitis, cholestasis, ulcerative colitis, hepatocellular and colorectal cancer. The drug action is mediated through its interaction with the gut microbiota, modulation of several signalling pathways and inflammatory factors. The limitations of low solubility, permeability and bioavailability pose challenges in the therapeutic applications. The different modes of drug delivery used in the transport of baicalin for ready absorption have paved way for its use as a pharmacological agent against hepato-intestinal disorders. |
| Publish Date |
2022-07-13 07:30 |
| Citation |
Ganguly R, Gupta A, Pandey AK. Role of baicalin as a potential therapeutic agent in hepatobiliary and gastrointestinal disorders: A review. World J Gastroenterol 2022; 28(26): 3047-3062 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i26/3047.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i26.3047 |
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