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2/24/2023 9:09:47 AM | Browse: 144 | Download: 506
Publication Name World Journal of Clinical Cases
Manuscript ID 75182
Country/Territory United States
Received
2022-10-30 05:47
Peer-Review Started
2022-10-30 05:48
To Make the First Decision
Return for Revision
2022-11-28 04:46
Revised
2022-12-17 00:34
Second Decision
2023-02-03 03:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-02-03 07:09
Articles in Press
2023-02-03 07:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-01-13 01:32
Typeset the Manuscript
2023-02-14 15:14
Publish the Manuscript Online
2023-02-24 09:09
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Retrospective Study
Article Title Hyperglycemia in COVID-19 infection without diabetes mellitus: Association with inflammatory markers
Manuscript Source Invited Manuscript
All Author List Harinivaas Shanmugavel Geetha, Garima Singh, Abinesh Sekar, Maya Gogtay, Yuvaraj Singh, GM Abraham and Nitin Trivedi
ORCID
Author(s) ORCID Number
Harinivaas Shanmugavel Geetha http://orcid.org/0000-0001-6293-208X
Maya Gogtay http://orcid.org/0000-0001-9955-7121
Yuvaraj Singh http://orcid.org/0000-0003-4970-8870
GM Abraham http://orcid.org/0000-0003-4296-8362
Nitin Trivedi http://orcid.org/0000-0002-2510-8339
Funding Agency and Grant Number
Corresponding Author Yuvaraj Singh, MD, Chief Physician, Researcher, Internal Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA 01608, United States. yuvarajmle@gmail.com
Key Words COVID-19; Inflammatory markers; Hyperglycemia; C-reactive protein; Mortality; Severity; Mechanisms; Diabetes mellitus
Core Tip Our study suggests that there is no correlation between the inflammatory marker levels and the presence of hyperglycemia in non-diabetic patients with coronavirus disease 2019 (COVID-19) infection. With an increased need to understand the mechanism underlying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-induced hyperglycemia, we assessed the validity of the most accepted COVID-19 infection-induced cytokine storm-related stress hyperglycemia theory. However, our study did not show any correlation between inflammatory marker levels that correlate with the cytokine storm and the level of hyperglycemia. This suggests the possibility of other mechanisms playing a role in the SARS-CoV-2 infection-induced hyperglycemia. Our study also demonstrated that new-onset hyperglycemia was an independent risk factor for higher mortality and length of stay, thereby emphasizing the need to understand the mechanisms leading to hyperglycemia.
Publish Date 2023-02-24 09:09
Citation Geetha HS, Singh G, Sekar A, Gogtay M, Singh Y, Abraham GM, Trivedi N. Hyperglycemia in COVID-19 infection without diabetes mellitus: Association with inflammatory markers. World J Clin Cases 2023; 11(6): 1287-1298
URL https://www.wjgnet.com/2307-8960/full/v11/i6/1287.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i6.1287
Full Article (PDF) WJCC-11-1287.pdf
Full Article (Word) WJCC-11-1287.docx
Manuscript File 75182_Auto_Edited-FilipodiaCL-JLW.docx
Answering Reviewers 75182-Answering reviewers.pdf
Audio Core Tip 75182-Audio core tip.m4a
Biostatistics Review Certificate 75182-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 75182-Conflict-of-interest statement.pdf
Copyright License Agreement 75182-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 75182-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 75182-Institutional review board statement.pdf
Peer-review Report 75182-Peer-review(s).pdf
Scientific Misconduct Check 75182-Bing-Liu GL-2.png
Scientific Editor Work List 75182-Scientific editor work list.pdf