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Articles Published Processes
8/3/2022 7:54:39 AM | Browse: 311 | Download: 598
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Received |
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2022-01-18 02:18 |
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Peer-Review Started |
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2022-01-18 02:19 |
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To Make the First Decision |
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Return for Revision |
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2022-04-11 06:54 |
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Revised |
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2022-04-24 14:55 |
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Second Decision |
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2022-07-01 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-06 03:12 |
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Articles in Press |
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2022-07-06 03:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-07-25 02:39 |
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Publish the Manuscript Online |
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2022-08-03 07:54 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Mechanistic and functional extrapolation of SET and MYND domain-containing protein 2 to pancreatic cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Eid Alshammari, Ying-Xue Zhang and Zhe Yang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Zhe Yang, PhD, Associate Professor, Department of Biochemistry, Microbiology, and Immunology, Wayne State University School of Medicine , 540 E Canfield St, Detroit, MI 48201, United States. zyang@med.wayne.edu |
| Key Words |
Pancreatic ductal adenocarcinoma; Protein lysine methyltransferase; Histone/non-histone methylation; Oncogenic signaling pathways; Methyltransferase inhibitors |
| Core Tip |
The broad substrate specificity of SET and MYND domain-containing protein 2 (SMYD2) and its involvement in diverse oncogenic signaling pathways in numerous cancers have provided a wealth of information that could be extrapolated to the pancreatic ductal adenocarcinoma (PDAC) research field to expand our understanding of SMYD2 in PDAC development. This review not only discusses the known roles of SMYD2 in PDAC initiation and progression, but also aims to capitalize on a rich body of knowledge with respect to SMYD2’s involvement in various signaling cascades to develop new hypotheses about the mechanisms of driving PDAC tumor growth and metastasis. |
| Publish Date |
2022-08-03 07:54 |
| Citation |
Alshammari E, Zhang YX, Yang Z. Mechanistic and functional extrapolation of SET and MYND domain-containing protein 2 to pancreatic cancer. World J Gastroenterol 2022; 28(29): 3753-3766 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i29/3753.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i29.3753 |
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