Publication Name	World Journal of Clinical Cases
Manuscript ID	75439
Country	China

Received	2022-02-08 12:38
Peer-Review Started	2022-02-08 12:39
To Make the First Decision
Return for Revision	2022-05-11 09:22
Revised	2022-05-18 19:13
Second Decision	2022-06-20 03:04
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-06-26 22:41
Articles in Press	2022-06-26 22:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-07-13 02:42
Publish the Manuscript Online	2022-07-22 07:03

ISSN	2307-8960 (online)
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Category	Hematology
Manuscript Type	Case Report
Article Title	Occurrence of MYD88L265P and CD79B mutations in diffuse large b cell lymphoma with bone marrow infiltration: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Ye Huang and Zhi-Yun Weng
ORCID	Author(s) ORCID Number Wen-Ye Huang http://orcid.org/0000-0002-4474-3469 Zhi-Yun Weng http://orcid.org/0000-0002-0914-249X
Funding Agency and Grant Number
Corresponding Author	Zhi-Yun Weng, MD, Chief Doctor, Department of Hematology, The Affiliated Yueqing Hospital of Wenzhou Medical University, No. 338 Qingyuan Road, Yueqing 325600, Zhejiang Province, China. weng_zhi_yun@163.com
Key Words	Bone marrow infiltration; Case report; CD79B; Diffuse large B cell lymphoma; Ibrutinib; MYD88L265P
Core Tip	This report highlights the possible transformation from Waldenstrom macroglobulinemia (WM) to diffuse large B cell lymphoma (DLBCL). Bone marrow infiltration by small lymphocytes, with an immunophenotype compatible with WM and the presence of MYD88L265P and CD79B mutations, support the hypothesis that the case may have transformed from lymphoplasmic lymphoma/WM. The CD79B mutation may be a potential biomarker for predicting the conversion of WM to DLBCL. Understanding the biology and mechanisms behind this process is important to identify susceptible patients. Frail patients could benefit from personalized low toxicity therapeutic approaches based on their mutational profile.
Publish Date	2022-07-22 07:03
Citation	Huang WY, Weng ZY. Occurrence of MYD88L265P and CD79B mutations in diffuse large b cell lymphoma with bone marrow infiltration: A case report. World J Clin Cases 2022; 10(22): 7994-8002
URL	https://www.wjgnet.com/2307-8960/full/v10/i22/7994.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i22.7994

Full Article (PDF)	WJCC-10-7994.pdf
Full Article (Word)	WJCC-10-7994.docx
CARE Checklist–2016	75439-CARE-Checklist–2016-revision.pdf
Manuscript File	75439_Auto_Edited-YJM-LS.docx
Answering Reviewers	75439-Answering reviewers.pdf
Audio Core Tip	75439-Audio core tip.wav
Conflict-of-Interest Disclosure Form	75439-Conflict-of-interest statement.pdf
Copyright License Agreement	75439-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	75439-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	75439-Language certificate.pdf
Peer-review Report	75439-Peer-review(s).pdf
Scientific Editor Work List	75439-Scientific editor work list.pdf
CrossCheck Report	75439-CrossCheck report.pdf