Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	7562
Country	Israel

Received	2013-11-25 14:41
Peer-Review Started	2013-11-25 21:21
To Make the First Decision	2013-12-25 18:10
Return for Revision	2013-12-26 20:22
Revised
Second Decision	2014-04-11 18:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-11 19:01
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-13 20:27
Publish the Manuscript Online	2014-05-14 20:01

ISSN	1948-5204 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Modulators affecting the immune dialogue between human immune and colon cancer cells
Manuscript Source	Invited Manuscript
All Author List	Meir Djaldetti and Hanna Bessler
Funding Agency and Grant Number
Corresponding Author	Meir Djaldetti, MD, Professor of Medicine, The Laboratory for Immunology and Hematology Research, Rabin Medical Center, Hasharon Hospital, 7 Keren Kayemet St., 49372 Petah-Tiqva, Israel. meird@clalit.org.il
Key Words	Cytokines; Immune dialogue; Colon cancer; Peripheral blood mononuclear cells; Cross-talk
Core Tip	The substantial number of studies that soundly demonstrated the close relationship between chronic inflammation and colon carcinogenesis has encouraged researchers to investigate the pathways interrelated with this process. The results point-out to various factors, molecules and genes that may jointly enhance or inhibit tumor development. The close linkage between immune and colon cancer cells resulting in a cross-talk between them with a consequent equilibrium in inflammatory cytokines release opens a new window for understanding the complicated stages of cancer initiation and progression. Moreover, the capability of emerging modulators to target the dialogue between immune and cancer cells indicates that immunomodulation may serve as a promising addition to the drug armamentarium for colorectal cancer.
Publish Date	2014-05-14 20:01
Citation	Djaldetti M, Bessler H. Modulators affecting the immune dialogue between human immune and colon cancer cells. World J Gastrointest Oncol 2014; 6(5): 129-138
URL	http://www.wjgnet.com/1948-5204/full/v6/i5/129.htm
DOI	http://dx.doi.org/10.4251/wjgo.v6.i5.129

Full Article (PDF)	WJGO-6-129.pdf
Full Article (Word)	WJGO-6-129.doc
Manuscript File	7562-Review.docx
Answering Reviewers	7562-Answering reviewers.pdf
Copyright License Agreement	7562-Copyright assignment.pdf
Peer-review Report	7562-Peer review(s).pdf
Scientific Editor Work List	7562-Scientific editor work list.doc