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Articles Published Processes
11/15/2022 10:19:35 AM | Browse: 316 | Download: 944
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Received |
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2022-05-04 05:50 |
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Peer-Review Started |
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2022-05-04 05:53 |
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To Make the First Decision |
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Return for Revision |
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2022-07-14 17:17 |
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Revised |
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2022-08-19 10:56 |
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Second Decision |
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2022-09-19 03:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-09-21 18:08 |
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Articles in Press |
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2022-09-21 18:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-09-06 01:58 |
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Typeset the Manuscript |
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2022-09-27 15:55 |
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Publish the Manuscript Online |
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2022-11-15 10:19 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Case Control Study |
Article Title |
Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Dimitrios Tsounis, Vassiliki Villiotou, Angeliki Melpidou, Chara Pantsiou, Alexandra Argyrou, Charis Giannopoulou, Adriani Grigoratou, Dimitra Rontogianni, Gerassimos J Mantzaris and George Papatheodoridis |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Dimitrios Tsounis, FEBG, MD, MSc, Chief Doctor, Consultant Physician-Scientist, Department of Gastroenterology, 251 General Hospital of Hellenic Air Force, P. Kanellopoulou Avenue 3, Athens 11525, Greece. dim.tsoun69@gmail.com |
Key Words |
Oxidative imbalance; Reactive oxygen species; Colorectal adenocarcinoma; Colonic polyps; Antioxidant capacity |
Core Tip |
The role of oxidative stress in the pathogenesis of colorectal carcinoma (CRC) has garnered considerable interest recently. Here, we evaluated oxidant activity and antioxidant capacity of the patients with serum measurements of specific markers. Increased levels of vitamin E, vitamin D, selenium and zinc seem to bestow a protective effect regarding the development of CRC, whereas elevated serum levels of malondialdehyde are associated with a higher risk of CRC. Increased oxidative stress may play an important role in the pathogenesis and progression of CRC. Antioxidants’ presence may exert a protective effect in the very early stages of colon carcinogenesis. |
Publish Date |
2022-11-15 10:19 |
Citation |
Tsounis D, Villiotou V, Melpidou A, Pantsiou C, Argyrou A, Giannopoulou C, Grigoratou A, Rontogianni D, Mantzaris GJ, Papatheodoridis G. Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development. World J Gastrointest Oncol 2022; 14(11): 2208-2223 |
URL |
https://www.wjgnet.com/1948-5204/full/v14/i11/2208.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v14.i11.2208 |
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