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11/15/2022 10:19:35 AM | Browse: 193 | Download: 453
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 75851
Country Greece
Received
2022-05-04 05:50
Peer-Review Started
2022-05-04 05:53
To Make the First Decision
Return for Revision
2022-07-14 17:17
Revised
2022-08-19 10:56
Second Decision
2022-09-19 03:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-09-21 18:08
Articles in Press
2022-09-21 18:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-09-06 01:58
Typeset the Manuscript
2022-09-27 15:55
Publish the Manuscript Online
2022-11-15 10:19
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Control Study
Article Title Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development
Manuscript Source Unsolicited Manuscript
All Author List Dimitrios Tsounis, Vassiliki Villiotou, Angeliki Melpidou, Chara Pantsiou, Alexandra Argyrou, Charis Giannopoulou, Adriani Grigoratou, Dimitra Rontogianni, Gerassimos J Mantzaris and George Papatheodoridis
ORCID
Author(s) ORCID Number
Dimitrios Tsounis http://orcid.org/0000-0001-7453-7677
Vassiliki Villiotou http://orcid.org/0000-0002-0990-7448
Angeliki Melpidou http://orcid.org/0000-0002-2785-3789
Chara Pantsiou http://orcid.org/0000-0002-6810-1743
Alexandra Argyrou http://orcid.org/0000-0002-1569-5592
Charis Giannopoulou http://orcid.org/0000-0002-4068-3120
Adriani Grigoratou http://orcid.org/0000-0002-5765-5265
Dimitra Rontogianni http://orcid.org/0000-0003-3723-2924
Gerassimos J Mantzaris http://orcid.org/0000-0002-5302-5450
George Papatheodoridis http://orcid.org/0000-0002-3518-4060
Funding Agency and Grant Number
Corresponding Author Dimitrios Tsounis, FEBG, MD, MSc, Chief Doctor, Consultant Physician-Scientist, Department of Gastroenterology, 251 General Hospital of Hellenic Air Force, P. Kanellopoulou Avenue 3, Athens 11525, Greece. dim.tsoun69@gmail.com
Key Words Oxidative imbalance; Reactive oxygen species; Colorectal adenocarcinoma; Colonic polyps; Antioxidant capacity
Core Tip The role of oxidative stress in the pathogenesis of colorectal carcinoma (CRC) has garnered considerable interest recently. Here, we evaluated oxidant activity and antioxidant capacity of the patients with serum measurements of specific markers. Increased levels of vitamin E, vitamin D, selenium and zinc seem to bestow a protective effect regarding the development of CRC, whereas elevated serum levels of malondialdehyde are associated with a higher risk of CRC. Increased oxidative stress may play an important role in the pathogenesis and progression of CRC. Antioxidants’ presence may exert a protective effect in the very early stages of colon carcinogenesis.
Publish Date 2022-11-15 10:19
Citation Tsounis D, Villiotou V, Melpidou A, Pantsiou C, Argyrou A, Giannopoulou C, Grigoratou A, Rontogianni D, Mantzaris GJ, Papatheodoridis G. Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development. World J Gastrointest Oncol 2022; 14(11): 2208-2223
URL https://www.wjgnet.com/1948-5204/full/v14/i11/2208.htm
DOI https://dx.doi.org/10.4251/wjgo.v14.i11.2208
Full Article (PDF) WJGO-14-2208.pdf
Full Article (Word) WJGO-14-2208.docx
STROBE Statement 75851-STROBE-Statement-revision.pdf
Manuscript File 75851_Auto_Edited-LM.docx
Answering Reviewers 75851-Answering reviewers.pdf
Audio Core Tip 75851-Audio core tip.mp3
Biostatistics Review Certificate 75851-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 75851-Conflict-of-interest statement.pdf
Copyright License Agreement 75851-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 75851-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 75851-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 75851-Language certificate.pdf
Peer-review Report 75851-Peer-review(s).pdf
Scientific Editor Work List 75851-Scientific editor work list.pdf