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Articles Published Processes
7/20/2022 7:37:19 AM | Browse: 443 | Download: 799
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Received |
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2022-03-01 04:50 |
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Peer-Review Started |
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2022-03-01 04:51 |
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To Make the First Decision |
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Return for Revision |
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2022-04-19 01:24 |
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Revised |
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2022-05-03 00:38 |
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Second Decision |
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2022-06-10 03:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-06-17 22:40 |
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Articles in Press |
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2022-06-17 22:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-06-29 11:01 |
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Publish the Manuscript Online |
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2022-07-20 07:37 |
ISSN |
2222-0682 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Minireviews |
Article Title |
Gut microbiota interactions with anti-diabetic medications and pathogenesis of type 2 diabetes mellitus
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Manuscript Source |
Invited Manuscript |
All Author List |
Ravi Kant, Lakshya Chandra, Vipin Verma, Priyanshu Nain, Diego Bello, Siddharth Patel, Subash Ala, Rashmi Chandra and Mc Anto Antony |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ravi Kant, MD, Associate Professor, Department of Endocrinology, Diabetes and Metabolism, Medical University of South Carolina, 2000 E Greenville Street, Suite 3100, Anderson, SC 29621, United States. kant.ravi.md@gmail.com |
Key Words |
Metabolic disease; Gut microbiota; Cardiovascular disease; Short chain fatty acid; Dysbiosis; Trimethylamine-N-oxide |
Core Tip |
Gut microbiota influence the pathogenesis of type 2 diabetes mellitus (T2DM) and metabolic syndrome through multiple mechanisms. The role of dysbiosis and various pathophysiological mechanisms such as altered metabolism of short-chain fatty acids, interaction with gut hormones, increased gut microbial metabolite trimethylamine-N-oxide (TMAO) and bacterial translocation in the pathogenesis of T2DM and cardio-metabolic diseases have been extensively studied. With increasing evidence regarding the significance of gut microbiota, it is imperative to review the role of gut microbiota in the pathogenesis of T2DM. This review also discusses the interaction between gut microbiota and the various medications used in the treatment of T2DM. |
Publish Date |
2022-07-20 07:37 |
Citation |
Kant R, Chandra L, Verma V, Nain P, Bello D, Patel S, Ala S, Chandra R, Antony MA. Gut microbiota interactions with anti-diabetic medications and pathogenesis of type 2 diabetes mellitus. World J Methodol 2022; 12(4): 246-257 |
URL |
https://www.wjgnet.com/2222-0682/full/v12/i4/246.htm |
DOI |
https://dx.doi.org/10.5662/wjm.v12.i4.246 |
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