| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Prognostic impact of tumor deposits on overall survival in colorectal cancer: Based on Surveillance, Epidemiology, and End Results database
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Xiao Wu, Da-Kui Zhang, Shao-Xuan Chen, Zhi-Yong Hou, Bai-Long Sun, Li Yao and Jian-Zheng Jie |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Scientific and Technological Project of Qinghai Province |
2015-ZJ-742 |
|
| Corresponding Author |
Jian-Zheng Jie, MD, Doctor, Doctor, Colorectal Surgery, China-Japan Friendship Hospital, No. 2, Yinghuayuan East Street, Chaoyang District, Beijing 100029, China. dakuizhang2021@126.com |
| Key Words |
Extranodal extension; Colorectal neoplasms; Prognosis; Neoplasm staging; Surveillance, Epidemiology, and End Results program |
| Core Tip |
We evaluated the predictive value of tumor deposits (TDs) for overall survival (OS) in patients with colorectal cancer based on a collection of 103755 patients derived from Surveillance, Epidemiology, and End Results database, including TD-negative and TD-positive subpopulations with Cox proportional hazard model. The sensitivity analyses were performed to detect outcome robustness. TD was an independent prognostic factor for OS. We also performed exploratory analysis to evaluate the effect of TD addition to the lymph node metastases count in tumor, node and metastasis-stage III subpopulations. The outcomes of subgroup analysis investigating the different risk factor profiles indicated that TDs may affect survival through more than one approach. |
| Publish Date |
2022-09-09 12:48 |
| Citation |
Wu WX, Zhang DK, Chen SX, Hou ZY, Sun BL, Yao L, Jie JZ. Prognostic impact of tumor deposits on overall survival in colorectal cancer: Based on Surveillance, Epidemiology, and End Results database. World J Gastrointest Oncol 2022; 14(9): 1699-1710 |
| URL |
https://www.wjgnet.com/1948-5204/full/v14/i9/1699.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i9.1699 |
