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Articles Published Processes
8/16/2022 1:35:31 AM | Browse: 183 | Download: 515
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Received |
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2022-03-21 11:27 |
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Peer-Review Started |
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2022-03-21 11:29 |
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To Make the First Decision |
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Return for Revision |
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2022-05-01 13:01 |
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Revised |
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2022-05-14 06:57 |
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Second Decision |
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2022-07-13 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-07-17 23:09 |
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Articles in Press |
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2022-07-17 23:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-08-02 02:13 |
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Publish the Manuscript Online |
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2022-08-16 01:35 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Pyroptosis-related genes play a significant role in the prognosis of gastric cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shi-Hao Guan, Xin-Yu Wang, Ping Shang, Qian-Cheng Du, Ming-Zhi Li, Xiao Xing and Bin Yan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bin Yan, PhD, Chief Doctor, Professor, Department of General Surgery, the Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, No. 1158 Gongyuan East Road, Shanghai 201700, China. yanbin202203@163.com |
| Key Words |
Gastric cancer; Pyroptosis; Gene signature; Overall survival |
| Core Tip |
This study aims to evaluate the expression of pyroptosis-related genes in gastric cancer (GC) and its correlation with prognosis. Based on 63 pyroptosis differentially expressed genes, 5 gene signature were constructed and all GC patients were classified into two risk groups. Kaplan-Meier survival curve showed that the overall survival (OS) of patients in the high-risk group was significantly lower than that of the low-risk group. Multivariate Cox regression analyses showed that the risk score was an independent risk factor for OS. The immune function and immune cell scores of the high-risk group were generally higher than those of the low-risk group. Similar results were obtained in external validation. |
| Publish Date |
2022-08-16 01:35 |
| Citation |
Guan SH, Wang XY, Shang P, Du QC, Li MZ, Xing X, Yan B. Pyroptosis-related genes play a significant role in the prognosis of gastric cancer. World J Clin Cases 2022; 10(24): 8490-8505 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i24/8490.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i24.8490 |
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