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Articles Published Processes
8/3/2022 9:47:21 AM | Browse: 299 | Download: 721
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Received |
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2022-04-02 17:49 |
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Peer-Review Started |
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2022-04-02 17:50 |
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To Make the First Decision |
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Return for Revision |
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2022-05-31 02:52 |
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Revised |
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2022-06-14 02:25 |
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Second Decision |
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2022-07-13 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-17 23:52 |
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Articles in Press |
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2022-07-17 23:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-07-31 23:55 |
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Publish the Manuscript Online |
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2022-08-03 09:47 |
| ISSN |
2220-6132 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Clinical Neurology |
| Manuscript Type |
Basic Study |
| Article Title |
Cell-free mitochondrial DNA quantification in ischemic stroke patients for non-invasive and real-time monitoring of disease status
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Nusrath Fathima, Sandhya Manorenj, Sandeep Kumar Vishwakarma and Aleem Ahmed Khan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Aleem Ahmed Khan, PhD, Senior Scientist, Central Laboratory for Stem Cell Research and Translational Medicine, Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad 500058, Telangana, India. aleem_a_khan@rediffmail.com |
| Key Words |
Cell-free mitochondrial DNA; NADH-ubiquinone oxidoreductase chain 1; Ischemic stroke; Circulating biomarker; National Institute of Health Stroke Scale score; Stroke assessment; Severity and outcome |
| Core Tip |
Several blood biomarkers have been studied to determine the severity and outcome of ischemic stroke with limited applications. Hence, we need to establish molecular markers which can provide more comprehensive information on the stroke pathophysiology and treatment response. Dynamic quantification of plasma cell-free DNA appears to be a valid and reliable option. Hence, we compared the real-time expression of cell-free mitochondrial DNA (NADH-ubiquinone oxidoreductase chain 1 gene) in ischemic stroke patients with healthy controls and studies its prognostic value during the treatment. This study could aid in the development of clinical values for assessing real-time, non-invasive mode of ischemic stroke status in the future. |
| Publish Date |
2022-08-03 09:47 |
| Citation |
Fathima N, Manorenj S, Vishwakarma SK, Khan AA. Cell-free mitochondrial DNA quantification in ischemic stroke patients for non-invasive and real-time monitoring of disease severity and outcome. World J Transl Med 2022; 10(2):14-28 |
| URL |
https://www.wjgnet.com/2220-3230/full/v10/i2/14.htm |
| DOI |
https://dx.doi.org/10.5528/wjtm.v10.i2.14 |
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