| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Family-based Helicobacter pylori infection status and transmission pattern in central China, and its clinical implications for disease prevention
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xue-Chun Yu, Qiao-Qiao Shao, Jing Ma, Miao Yu, Chen Zhang, Lei Lei, Yang Zhou, Wen-Chao Chen, Wei Zhang, Xin-Hui Fang, Yuan-Zeng Zhu, Gang Wu, Xue-Mei Wang, Shuang-Yin Han, Pei-Chun Sun and Song-Ze Ding |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
U1604174 |
| Henan Provincial Government-Health and Family Planning Commission |
20170123 |
| Henan Provincial Government-Health and Family Planning Commission |
SBGJ202002004 |
| Henan Provincial Government-Health and Family Planning Commission Research Innovative Talents Project |
51282 |
|
| Corresponding Author |
Song-Ze Ding, MD, PhD, Professor, Department of Gastroenterology and Hepatology, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, No. 7 Weiwu Road, Jin Shui District, Zhengzhou 450003, Henan Province, China. dingsongze@hotmail.com |
| Key Words |
Helicobacter pylori; Atrophic gastritis; Family clustering infection; Gastric cancer; Gastrin; Pepsinogen |
| Core Tip |
Helicobacter pylori (H. pylori) has characteristics of family cluster infection. However, few studies have investigated family-based infection status and pattern of intrafamilial transmission in the general public of central China. In our study, the H. pylori infection rate was 54.27%, but in 87.23% of healthy households, there was at least 1 H. pylori-infected person; in 27.24% of these infected families, all members were infected. Type I H. pylori was the dominant strain in this area. Intrafamilial infection status and patterns of transmission are important causes of H. pylori spread, indicating the urgent need for family-based infection control and related disease prevention. |
| Publish Date |
2022-07-27 02:48 |
| Citation |
Yu XC, Shao QQ, Ma J, Yu M, Zhang C, Lei L, Zhou Y, Chen WC, Zhang W, Fang XH, Zhu YZ, Wu G, Wang XM, Han SY, Sun PC, Ding SZ. Family-based Helicobacter pylori infection status and transmission pattern in central China, and its clinical implications for disease prevention. World J Gastroenterol 2022; 28(28): 3706-3719 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i28/3706.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i28.3706 |
