Publication Name	World Journal of Gastroenterology
Manuscript ID	7745
Country	Switzerland

Received	2013-11-30 12:32
Peer-Review Started	2013-11-30 13:42
To Make the First Decision	2014-01-15 19:13
Return for Revision	2014-01-20 22:26
Revised
Second Decision	2014-04-09 09:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-09 09:39
Articles in Press	2014-05-23 09:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-12 18:54
Publish the Manuscript Online	2014-07-03 15:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Portopulmonary hypertension and hepatopulmonary syndrome
Manuscript Source	Invited Manuscript
All Author List	Florence Aldenkortt, Marc Aldenkortt, Laurence Caviezel, Jean Luc Waeber, Anne Weber and Eduardo Schiffer
Funding Agency and Grant Number
Corresponding Author	Florence Aldenkortt, MD, Staff Anesthesiologist, Division of Anesthesiology, Department of Anesthesiology, Clinical Pharmacology and Intensive Care, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva, Switzerland. florence.aldenkortt@hcuge.ch
Key Words	End stage liver disease; Hepatopulmonary syndrome; Portopulmonary Hypertension; Anesthesia
Core Tip	Portopulmonary hypertension (POPH) and hepatopulmonary syndrome (HPS) are frequent complications of liver disease. Both conditions result from diminished hepatic clearance of splanchnic vasoactive substances. They cause pulmonary vasoconstriction in POPH resulting in elevated pulmonary pressure, right ventricular dysfunction and intrapulmonary shunts with hypoxemia in HPS. The only lasting treatment is liver transplantation (LT). Whereas LT results in the disappearance of HPS, its effect on POPH is unpredictable. The anesthesiologist plays a central role in managing HPS and POPH during LT as preoperative screening and grading of the disease allows the selection of appropriate therapies.
Publish Date	2014-07-03 15:30
Citation	Aldenkortt F, Aldenkortt M, Caviezel L, Waeber JL, Weber A, Schiffer E. Portopulmonary hypertension and hepatopulmonary syndrome. World J Gastroenterol 2014; 20(25): 8072-8081
URL	http://www.wjgnet.com/1007-9327/full/v20/i25/8072.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i25.8072

Full Article (PDF)	WJG-20-8072.pdf
Full Article (Word)	WJG-20-8072.doc
Manuscript File	7745-Review.docx
Answering Reviewers	7745-Answering reviewers.pdf
Copyright License Agreement	7745-Copyright assignment.pdf
Peer-review Report	7745-Peer review(s).pdf
Scientific Editor Work List	7745-Scientific editor work list.doc