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10/27/2022 4:55:05 AM | Browse: 152 | Download: 342
Publication Name World Journal of Clinical Cases
Manuscript ID 77540
Country China
Received
2022-05-31 15:09
Peer-Review Started
2022-05-31 15:13
To Make the First Decision
Return for Revision
2022-07-14 08:24
Revised
2022-08-01 15:23
Second Decision
2022-09-20 03:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-09-21 00:15
Articles in Press
2022-09-21 00:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-09-18 09:51
Typeset the Manuscript
2022-10-18 07:06
Publish the Manuscript Online
2022-10-27 04:55
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Clinical Trials Study
Article Title Dan Bai Xiao Formula combined with glucocorticoids and cyclophosphamide for pediatric lupus nephritis: A pilot prospective study
Manuscript Source Unsolicited Manuscript
All Author List Tong-Tong Cao, Li Chen, Xiao-Fang Zhen, Gao-Jie Zhao, Hui-Fang Zhang and Yan Hu
ORCID
Author(s) ORCID Number
Yan Hu http://orcid.org/0000-0003-1255-6797
Funding Agency and Grant Number
Funding Agency Grant Number
Capital Health Research and Development of Special No. CH2018-2-2092
Corresponding Author Yan Hu, MD, PhD, Director, Doctor, Department of Traditional Chinese Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56 Nanlishi Road, Beijing 100045, China. huyan13370115073@163.com
Key Words Lupus nephritis; Traditional Chinese medicine; Dan Bai Xiao Formula; Effective; Safe
Core Tip Lupus nephritis (LN) is the most common and serious complication of systemic lupus erythematosus. Glucocorticoids (GCs) and immunosuppressants were considered routine treatments for patients with LN. However, there is a widespread consensus regarding the toxicity of immunosuppressive agents and the necessity of preventing children from taking these medications over an extended period. Accordingly, there is an increasing need for holistic and optimal therapy that results in a higher rate of remission and fewer side effects. Our study suggests that Dan Bai Xiao Formula (DBXF) treatment is effective and safe as a supplementary therapy for LN; moreover, this treatment is superior to routine GC and cyclophosphamide therapies. DBXF containing combination treatment may lead to faster proteinuria and hematuria resolution, smoother GC reduction, fewer methylprednisolone pulses, and fewer adverse events.
Publish Date 2022-10-27 04:55
Citation Cao TT, Chen L, Zhen XF, Zhao GJ, Zhang HF, Hu Y. Dan Bai Xiao Formula combined with glucocorticoids and cyclophosphamide for pediatric lupus nephritis: A pilot prospective study. World J Clin Cases 2022; 10(31): 11391-11402
URL https://www.wjgnet.com/2307-8960/full/v10/i31/11391.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i31.11391
Full Article (PDF) WJCC-10-11391.pdf
Full Article (Word) WJCC-10-11391.docx
CONSORT 2010 Statement 77540-CONSORT-2010-Statement-revision.pdf
Manuscript File 77540_Auto_Edited-YLC-Wang TQ-JLW.docx
Answering Reviewers 77540-Answering reviewers.pdf
Audio Core Tip 77540-Audio core tip.wav
Biostatistics Review Certificate 77540-Biostatistics statement.pdf
Clinical Trial Registration Statement 77540-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 77540-Conflict-of-interest statement.pdf
Copyright License Agreement 77540-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 77540-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 77540-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 77540-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 77540-Language certificate.pdf
Peer-review Report 77540-Peer-review(s).pdf
Scientific Misconduct Check 77540-Bing-Chen YL-2.png
Scientific Editor Work List 77540-Scientific editor work list.pdf