Publication Name	World Journal of Gastroenterology
Manuscript ID	77596
Country	India

Received	2022-05-08 13:29
Peer-Review Started	2022-05-08 13:32
To Make the First Decision
Return for Revision	2022-06-08 06:45
Revised	2022-06-20 14:39
Second Decision	2022-09-09 03:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-09-12 17:43
Articles in Press	2022-09-12 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-09-07 13:17
Typeset the Manuscript	2022-09-15 08:42
Publish the Manuscript Online	2022-09-23 10:13

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Nonalcoholic steatohepatitis and hepatocellular carcinoma: Beyond the boundaries of the liver
Manuscript Source	Unsolicited Manuscript
All Author List	Tarana Gupta
ORCID	Author(s) ORCID Number Tarana Gupta http://orcid.org/0000-0003-3453-2040
Funding Agency and Grant Number
Corresponding Author	Tarana Gupta, Doctor, MBBS, MD, Professor, Department of Medicine, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Medical Mor, Rohtak 124001, Haryana, India. taranagupta@gmail.com
Key Words	Non-alcoholic steatohepatitis; Hepatocellular carcinoma; Cirrhosis; Genetic factors; Lifestyle factors; Surveillance
Core Tip	Nonalcoholic steatohepatitis (NASH) is a metabolic liver disease which also involves multiple organs like the heart, lungs, and kidneys. NASH may arise primarily, followed by involvement of other organs, or it may come late in the course of metabolic syndrome. The multidisciplinary approach is needed towards a patient with diabetes, obesity, and metabolic syndrome to address all issues related to the liver, heart, etc. Genetic and molecular signatures have provided a ray of hope for estimating risk in these patients; however, it has many practical issues. The impact of environmental pollutants and toxins as a causative factor in NASH, especially lean patient population, should also be considered. We need population based studies from different geographical areas for estimation of metabolic, environmental, and genetic risk factors.
Publish Date	2022-09-23 10:13
Citation	Gupta T. Nonalcoholic steatohepatitis and hepatocellular carcinoma: Beyond the boundaries of the liver. World J Gastroenterol 2022; 28(36): 5380-5382
URL	https://www.wjgnet.com/1007-9327/full/v28/i36/5380.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i36.5380

Full Article (PDF)	WJG-28-5380.pdf
Full Article (Word)	WJG-28-5380.docx
Manuscript File	77596_Auto_Edited-YLC-Wang TQ-LS.docx
Answering Reviewers	77596-Answering reviewers.pdf
Audio Core Tip	77596-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	77596-Conflict-of-interest statement.pdf
Copyright License Agreement	77596-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	77596-Language certificate.pdf
Peer-review Report	77596-Peer-review(s).pdf
Scientific Editor Work List	77596-Scientific editor work list.pdf
CrossCheck Report	77596-Bing-Chen YL-2.png
CrossCheck Report	77596-CrossCheck report.pdf