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Articles Published Processes
10/21/2022 2:24:59 AM | Browse: 371 | Download: 779
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Received |
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2022-05-12 03:58 |
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Peer-Review Started |
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2022-05-12 04:00 |
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To Make the First Decision |
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Return for Revision |
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2022-06-16 02:54 |
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Revised |
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2022-07-09 06:07 |
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Second Decision |
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2022-09-15 03:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-09-16 11:11 |
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Articles in Press |
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2022-09-16 11:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-09-07 12:57 |
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Typeset the Manuscript |
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2022-09-22 00:38 |
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Publish the Manuscript Online |
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2022-10-21 02:24 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Case Report |
Article Title |
Hypophysitis induced by anti-programmed cell death protein 1 immunotherapy in non-small cell lung cancer: Three case reports
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yun Zheng, Chen-Yu Zhu, Jing Lin, Wang-Shan Chen, Yu-Jie Wang, Hong-Ye Fu and Qiong Zhao |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Qiong Zhao, PhD, Doctor, Doctor, Zhejiang University School of Medicine, Zhejiang University, No. 866 Yuhangtang Road, Xihu District, Hangzhou 310030, Zhejiang Province, China. jade1972@126.com |
Key Words |
Programmed cell death protein 1; Immunotherapy; Hypophysitis; Lung cancer; Case reports |
Core Tip |
Hypophysitis induced by programmed cell death 1 protein (PD-1) inhibitor treatment in non-small cell lung cancer (NSCLC) was rarely reported. In this study, we report three patients with NSCLC who developed hypophysitis induced by PD-1 immune checkpoint inhibitor treatment. Our study suggested that unexpected fatigue, appetite decreases, nausea, vomiting, hoarse voice, bucking, and difficulty breathing were largely correlated with immune-related hypophysitis. We also found that the clinical prognosis of patients with hypophysitis was related to the dose of steroid therapy. This work provided a reference for the diagnosis and timely treatment of hypophysitis in the clinic. |
Publish Date |
2022-10-21 02:24 |
Citation |
Zheng Y, Zhu CY, Lin J, Chen WS, Wang YJ, Fu HY, Zhao Q. Hypophysitis induced by anti-programmed cell death protein 1 immunotherapy in non-small cell lung cancer: Three case reports. World J Clin Cases 2022; 10(30): 11049-11058 |
URL |
https://www.wjgnet.com/2307-8960/full/v10/i30/11049.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v10.i30.11049 |
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