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Articles Published Processes
9/16/2022 11:52:44 AM | Browse: 304 | Download: 987
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Received |
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2022-05-17 07:56 |
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Peer-Review Started |
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2022-05-17 07:59 |
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To Make the First Decision |
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Return for Revision |
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2022-06-16 08:14 |
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Revised |
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2022-06-30 00:49 |
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Second Decision |
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2022-08-19 03:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-21 17:54 |
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Articles in Press |
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2022-08-21 17:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-09-02 06:27 |
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Publish the Manuscript Online |
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2022-09-16 11:52 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Prognostic significance of sex determining region Y-box 2, E-cadherin, and vimentin in esophageal squamous cell carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chao Li and Yu-Qing Ma |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81860422 |
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| Corresponding Author |
Yu-Qing Ma, MD, Doctor, Doctor, Department of Pathology, The First Affiliated Hospital, Xinjiang Medical University, No. 137 Liyu Mountain South Road, Xinshi District, Urumqi 830054, Xinjiang Uygur Autonomous Region, China. 790701592@qq.com |
| Key Words |
Esophageal squamous cell carcinoma; Sex determining region Y-box 2; Epithelial-to-mesenchymal transition; Vimentin; E-cadherin |
| Core Tip |
Sex determining region Y-box 2 (SOX2) functions in the pathogenesis of squamous cell carcinoma (SSC) by driving the increase of tumor size and invasion, and is also associated with the expression of β-catenin and the epithelial-mesenchymal transition (EMT). Our examination of the role of SOX2 in esophageal SSC (ESCC) indicated that its expression had a positive correlation with vimentin expression, an established marker of the EMT. SOX2 expression was also associated the migration and invasion of ESCC, and this may be related to the upregulation of vimentin and the desreased expression of E-cadherin, which promote the EMT. SOX2 expression was an independent risk factor for poor OS in patients with ESCC. |
| Publish Date |
2022-09-16 11:52 |
| Citation |
Li C, Ma YQ. Prognostic significance of sex determining region Y-box 2, E-cadherin, and vimentin in esophageal squamous cell carcinoma. World J Clin Cases 2022; 10(27): 9657-9669 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i27/9657.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i27.9657 |
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