Publication Name	World Journal of Clinical Cases
Manuscript ID	77809
Country	China

Received	2022-05-21 15:19
Peer-Review Started	2022-05-21 15:20
To Make the First Decision
Return for Revision	2022-07-29 02:38
Revised	2022-08-12 00:42
Second Decision	2022-08-19 03:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-08-21 17:53
Articles in Press	2022-08-21 17:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-02 06:20
Publish the Manuscript Online	2022-09-16 11:52

ISSN	2307-8960 (online)
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Category	Neuroimaging
Manuscript Type	Case Report
Article Title	Familial mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episode syndrome: Three case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao Yang and Le-Jun Fu
ORCID	Author(s) ORCID Number Xiao Yang http://orcid.org/0000-0001-8453-5608 Le-Jun Fu http://orcid.org/0000-0003-0924-360X
Funding Agency and Grant Number
Corresponding Author	Le-Jun Fu, MM, Doctor, Doctor, Department of Medical Imaging, Tianjin Huanhu Hospital, No. 6 Jizhao Road, Jinnan District, Tianjin 300350, China. doctorfu20220505@163.com
Key Words	Mitochondrial encephalomyopathy; Magnetic resonance imaging; Genetic testing; Pathological results; Case report
Core Tip	Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episode (MELAS) syndrome is a hereditary metabolic disease with complex clinical manifestations, and is often misdiagnosed as cerebral infarction and encephalitis. When the patient has a family history of this disease, blood lactate level is higher than normal, and imaging examination suggests MELAS syndrome, the possibility of MELAS syndrome should be considered. The diagnosis should be confirmed by muscle biopsy and genetic testing.
Publish Date	2022-09-16 11:52
Citation	Yang X, Fu LJ. Familial mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episode syndrome: Three case reports. World J Clin Cases 2022; 10(27): 9945-9953
URL	https://www.wjgnet.com/2307-8960/full/v10/i27/9945.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i27.9945

Full Article (PDF)	WJCC-10-9945.pdf
Full Article (Word)	WJCC-10-9945.docx
CARE Checklist–2016	77809-CARE-Checklist–2016-revision.pdf
Manuscript File	77809_Auto_Edited-LS.docx
Answering Reviewers	77809-Answering reviewers.pdf
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CrossCheck Report	77809-CrossCheck report.pdf